Literature DB >> 8543178

Cloning and expression of a murine cDNA homologous to the human RCK/P54, a lymphoma-linked chromosomal translocation junction gene on 11q23.

M Seto1, K Yamamoto, T Takahashi, R Ueda.   

Abstract

The RCK/P54 gene was previously isolated from the chromosome translocation breakpoint region on 11q23 of a human lymphoma cell line, RC-K8, with t(11;14)(q23;q32). It was found to encode a 472-483-amino-acid (aa) polypeptide belonging to an RNA helicase/translation initiation factor family. The aim of the present investigation was the isolation and comparative sequence analysis of the mouse RCK/P54 cDNA from a BALB/c spleen cDNA library. Sequence analysis revealed an open reading frame (ORF) predicting a polypeptide of 483 aa showing 97.7% identity to human RCK/p54. Northern analysis demonstrated a 7.5-kb signal in all tissues tested and in vitro translation analysis showed a 54-kDa polypeptide. These results indicate that both mouse and human RCK/P54 are highly conserved.

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Year:  1995        PMID： 8543178     DOI： 10.1016/0378-1119(95)00559-5

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  7 in total

1.  Xp54, the Xenopus homologue of human RNA helicase p54, is an integral component of stored mRNP particles in oocytes.

Authors:  M Ladomery; E Wade; J Sommerville
Journal:  Nucleic Acids Res       Date:  1997-03-01       Impact factor: 16.971

2.  Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas.

Authors:  S Wang; I B Rosenwald; M J Hutzler; G A Pihan; L Savas; J J Chen; B A Woda
Journal:  Am J Pathol       Date:  1999-07       Impact factor: 4.307

3.  The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1.

Authors:  Nicole Fischer; Karsten Weis
Journal:  EMBO J       Date:  2002-06-03       Impact factor: 11.598

4.  The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

Authors:  J M Coller; M Tucker; U Sheth; M A Valencia-Sanchez; R Parker
Journal:  RNA       Date:  2001-12       Impact factor: 4.942

5.  A conserved role of a DEAD box helicase in mRNA masking.

Authors:  N Minshall; G Thom; N Standart
Journal:  RNA       Date:  2001-12       Impact factor: 4.942

Review 6.  Xp54 and related (DDX6-like) RNA helicases: roles in messenger RNP assembly, translation regulation and RNA degradation.

Authors:  Andrew Weston; John Sommerville
Journal:  Nucleic Acids Res       Date:  2006-06-12       Impact factor: 16.971

7.  Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae.

Authors:  Sandra Mota; Neide Vieira; Sónia Barbosa; Thierry Delaveau; Claire Torchet; Agnès Le Saux; Mathilde Garcia; Ana Pereira; Sophie Lemoine; Fanny Coulpier; Xavier Darzacq; Lionel Benard; Margarida Casal; Frédéric Devaux; Sandra Paiva
Journal:  PLoS One       Date:  2014-11-03       Impact factor: 3.240
  7 in total

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