M E Weisse1, B Eberly, D A Person. 1. Department of Paediatrics, Tripler Army Medical Center, Honolulu, HI 96859-5000, USA.
Abstract
OBJECTIVE: To test whether red and white wines are as potent as bismuth salicylate against the bacteria responsible for traveller's diarrhoea to try to explain wine's legendary reputation as a digestive aid. DESIGN: Red and white wine, bismuth salicylate, two solutions containing ethanol (diluted absolute ethanol and tequila), and sterilised water were tested against suspensions of salmonella, shigella, and Escherichia coli to determine relative antibacterial activity. Suspensions of 10(7) colony forming units of shigella, salmonella, and E coli were added to the test solutions and plated on standard nutrient agar at 0, 10, 20, 30, 60, and 120 minutes and 24 hours. Dilutions of wine and bismuth salicylate were then tested with E coli as the test bacterium, and the experiment repeated. MAIN OUTCOME MEASURES: Exposure times necessary for eradication of organisms for the different solutions; decreases in colony counts at the different exposure times for dilutions of wine and bismuth salicylates. RESULTS: Undiluted wine and bismuth salicylate were both effective in reducing the number of viable organisms (by 10(5)-10(6) colony forming units) after 20-30 minutes. Dilutions of wine were much more effective in decreasing colony counts than were similar dilutions of bismuth salicylate. CONCLUSION: The antibacterial property of wine is largely responsible for wine's reputation as a digestive aid.
OBJECTIVE: To test whether red and white wines are as potent as bismuth salicylate against the bacteria responsible for traveller's diarrhoea to try to explain wine's legendary reputation as a digestive aid. DESIGN: Red and white wine, bismuth salicylate, two solutions containing ethanol (diluted absolute ethanol and tequila), and sterilised water were tested against suspensions of salmonella, shigella, and Escherichia coli to determine relative antibacterial activity. Suspensions of 10(7) colony forming units of shigella, salmonella, and E coli were added to the test solutions and plated on standard nutrient agar at 0, 10, 20, 30, 60, and 120 minutes and 24 hours. Dilutions of wine and bismuth salicylate were then tested with E coli as the test bacterium, and the experiment repeated. MAIN OUTCOME MEASURES: Exposure times necessary for eradication of organisms for the different solutions; decreases in colony counts at the different exposure times for dilutions of wine and bismuth salicylates. RESULTS: Undiluted wine and bismuth salicylate were both effective in reducing the number of viable organisms (by 10(5)-10(6) colony forming units) after 20-30 minutes. Dilutions of wine were much more effective in decreasing colony counts than were similar dilutions of bismuth salicylate. CONCLUSION: The antibacterial property of wine is largely responsible for wine's reputation as a digestive aid.
Authors: H L DuPont; P Sullivan; D G Evans; L K Pickering; D J Evans; J J Vollet; C D Ericsson; P B Ackerman; W S Tjoa Journal: JAMA Date: 1980-01-18 Impact factor: 56.272
Authors: R Steffen; H L DuPont; R Heusser; A Helminger; F Witassek; M D Manhart; M Schär Journal: Antimicrob Agents Chemother Date: 1986-04 Impact factor: 5.191
Authors: L V Wood; L E Ferguson; P Hogan; D Thurman; D R Morgan; H L DuPont; C D Ericsson Journal: Appl Environ Microbiol Date: 1983-08 Impact factor: 4.792