Literature DB >> 8541662

Optical resolution of 1-arylethanols with a condensed aromatic ring by lipase from Pseudomonas aeruginosa.

K Kato1, M Katayama, S Fujii, H Kimoto.   

Abstract

Enantioselective syntheses of both enantiomers of 1-arylethanols with a condensed aromatic ring have been done through acetylation of the racemic alcohols with vinyl acetate in the presence of a lipase from Pseudomonas aeruginosa (Toyobo, LIP). The lipase LIP showed high enantioselectivity and reactivity for the title compounds, reacted acetates, and remaining alcohols were obtained with high optical purity.

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Year:  1995        PMID: 8541662     DOI: 10.1271/bbb.59.2178

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  1 in total

1.  Base-promoted lipase-catalyzed kinetic resolution of atropisomeric 1,1'-biaryl-2,2'-diols.

Authors:  Gamal A I Moustafa; Kengo Kasama; Koichi Higashio; Shuji Akai
Journal:  RSC Adv       Date:  2019-01-09       Impact factor: 4.036

  1 in total

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