Literature DB >> 8541350

Laser-excited fluorescence studies of mitochondrial function in saponin-skinned skeletal muscle fibers of patients with chronic progressive external ophthalmoplegia.

K Winkler1, A V Kuznetsov, H Lins, E Kirches, P von Bossanyi, K Dietzmann, B Frank, H Feistner, W S Kunz.   

Abstract

The functional behavior of mitochondria in skeletal muscle of patients with chronic progressive external ophthalmoplegia was studied by laser-excited fluorescence measurements of NAD(P)H and flavoproteins in saponin-skinned fibers. Variations in the mitochondrial content and the presence of partially respiratory chain-inhibited mitochondria can be detected using this novel method.

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Year:  1995        PMID： 8541350     DOI： 10.1016/0925-4439(95)00085-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

1.  Permeabilized rat cardiomyocyte response demonstrates intracellular origin of diffusion obstacles.

Authors:  Natalja Jepihhina; Nathalie Beraud; Mervi Sepp; Rikke Birkedal; Marko Vendelin
Journal:  Biophys J       Date:  2011-11-01       Impact factor: 4.033

2.  Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo.

Authors:  V A Saks; V I Veksler; A V Kuznetsov; L Kay; P Sikk; T Tiivel; L Tranqui; J Olivares; K Winkler; F Wiedemann; W S Kunz
Journal:  Mol Cell Biochem       Date:  1998-07       Impact factor: 3.396

3.  Detection of mitochondrial defects by laser fluorimetry.

Authors:  W S Kunz; K Winkler; A V Kuznetsov; H Lins; E Kirches; C W Wallesch
Journal:  Mol Cell Biochem       Date:  1997-09       Impact factor: 3.396

4.  Evaluation of quantitative and qualitative aspects of mitochondrial function in human skeletal and cardiac muscles.

Authors:  Benoit N'Guessan; Joffrey Zoll; Florence Ribera; Elodie Ponsot; Eliane Lampert; Renée Ventura-Clapier; Vladimir Veksler; Bertrand Mettauer
Journal:  Mol Cell Biochem       Date:  2004 Jan-Feb       Impact factor: 3.396

5.  Retinal flavoprotein autofluorescence as a measure of retinal health.

Authors:  Susan G Elner; Victor M Elner; Matthew G Field; Seung Park; John R Heckenlively; Howard R Petty
Journal:  Trans Am Ophthalmol Soc       Date:  2008

6.  Impaired mitochondrial oxidative phosphorylation in skeletal muscle of the dystrophin-deficient mdx mouse.

Authors:  A V Kuznetsov; K Winkler; F R Wiedemann; P von Bossanyi; K Dietzmann; W S Kunz
Journal:  Mol Cell Biochem       Date:  1998-06       Impact factor: 3.396
  6 in total

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