Literature DB >> 8539370

Squamous cell carcinomas that arise in the oral cavity and tongue base: can CT help predict perineural or vascular invasion?

S K Mukherji1, S M Weeks, M Castillo, B C Yankaskas, L A Krishnan, S Schiro.   

Abstract

PURPOSE: To determine the ability to use computed tomography (CT) to predict invasion of adjacent nerves or vessels by oral cavity tumors.
MATERIALS AND METHODS: Contrast material-enhanced CT scans and histopathologic reports were retrospectively reviewed in 48 patients (36 men, 12 women) aged 38-75 years who underwent gross total resection of squamous cell carcinomas arising in the tongue, the base of the tongue, and the floor of the mouth. CT criteria for diagnosis of perineural or vascular invasion were aggressive tumor margins, invasion of the sublingual space, and direct adjacency of the tumor to the enhanced lingual vasculature in the sublingual space. CT and histopathologic findings of perineural and/or vascular invasion by tumor were correlated in all patients.
RESULTS: With the above criteria, CT findings predictive of perineural or vascular invasion had a sensitivity of 88%; specificity, 83%; positive predictive value, 85%; and negative predictive value, 84%.
CONCLUSION: CT findings can be used to predict perineural or vascular invasion by oral cavity tumors.

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Year:  1996        PMID: 8539370     DOI: 10.1148/radiology.198.1.8539370

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  6 in total

1.  Perineural spread of adenoid cystic carcinoma in the oral and maxillofacial regions: evaluation with contrast-enhanced CT and MRI.

Authors:  H Shimamoto; J Chindasombatjaroen; N Kakimoto; M Kishino; S Murakami; S Furukawa
Journal:  Dentomaxillofac Radiol       Date:  2012-02       Impact factor: 2.419

Review 2.  [Cerebral nerves - perineural tumor spread].

Authors:  S Bisdas; M G Mack
Journal:  Radiologe       Date:  2009-07       Impact factor: 0.635

3.  Deep extension from carcinoma arising from the gingiva: CT and MR imaging features.

Authors:  Yasuo Kimura; Misa Sumi; Tadateru Sumi; Yoshiko Ariji; Eiichiro Ariji; Takashi Nakamura
Journal:  AJNR Am J Neuroradiol       Date:  2002-03       Impact factor: 3.825

Review 4.  CT-MR integrated diagnostic imaging of the oral cavity: neoplastic disease.

Authors:  S Mazziotti; G Ascenti; E Scribano; A Mileto; S Racchiusa; C Visalli; I Salamone; S Vinci; A Blandino
Journal:  Radiol Med       Date:  2012-03-19       Impact factor: 3.469

5.  Oropharyngeal cancer.

Authors:  Robert Hermans
Journal:  Cancer Imaging       Date:  2005-11-23       Impact factor: 3.909

6.  Subtraction iodine imaging with area detector CT to improve tumor delineation and measurability of tumor size and depth of invasion in tongue squamous cell carcinoma.

Authors:  Takashi Hiyama; Hirofumi Kuno; Kotaro Sekiya; So Tsushima; Shioto Oda; Tatsushi Kobayashi
Journal:  Jpn J Radiol       Date:  2021-09-16       Impact factor: 2.374

  6 in total

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