Cervical intraepithelial neoplasia in pregnancy.

There is no evidence that cervical intraepithelial neoplasia (CIN) progresses more rapidly because of pregnancy. Management of CIN in pregnancy, therefore, is conservative. Screening for invasive cancer is done at the first prenatal visit. Colposcopically directed biopsy can then be used to rule out invasive cancer. Postpartum cytology and colposcopy are important follow-up procedures for these women. Cryosurgery for CIN is usually contraindicated in pregnancy. This report includes examples of two pregnant patients with high-grade lesions. A diagnostic and treatment algorithm based on the current "expert opinion"is presented.