H Niimi1, T E Hartman, N L Müller. 1. Department of Radiology, University of British Columbia and Vancouver Hospital, Vancouver.
Abstract
OBJECTIVE: To describe the CT findings and corresponding pathological findings of necrotizing sarcoid granulomatosis (NSG). MATERIALS AND METHODS: We reviewed the high-resolution CT and macroscopic and histologic findings in three pathologically proven cases of NSG. RESULTS: The CT findings consisted of one case each with single nodule, multiple nodules, and parenchymal opacification. The abnormalities were peribronchovascular or subpleural in distribution. Histologically, all patients had sarcoid-like granulomas with central necrosis and granulomatous vasculitis. The CT findings correlated closely with the gross pathologic findings. CONCLUSION: We conclude that the CT manifestations of NSG reflect the variable macroscopic pathologic findings.
OBJECTIVE: To describe the CT findings and corresponding pathological findings of necrotizing sarcoid granulomatosis (NSG). MATERIALS AND METHODS: We reviewed the high-resolution CT and macroscopic and histologic findings in three pathologically proven cases of NSG. RESULTS: The CT findings consisted of one case each with single nodule, multiple nodules, and parenchymal opacification. The abnormalities were peribronchovascular or subpleural in distribution. Histologically, all patients had sarcoid-like granulomas with central necrosis and granulomatous vasculitis. The CT findings correlated closely with the gross pathologic findings. CONCLUSION: We conclude that the CT manifestations of NSG reflect the variable macroscopic pathologic findings.