Literature DB >> 8537270

Susceptibility of enterococci, methicillin-resistant Staphylococcus aureus and Streptococcus pneumoniae to the glycylcyclines.

W J Weiss1, N V Jacobus, P J Petersen, R T Testa.   

Abstract

The in-vitro activities of two glycylcyclines, DMG-MINO and DMG-DMDOT, and several comparative agents were determined against 263 enterococci, 102 methicillin-resistant Staphylococcus aureus and 55 Streptococcus pneumoniae recent clinical isolates. The glycylcyclines and teicoplanin were the most active agents against the enterococcal isolates. All methicillin-resistant S. aureus were susceptible to the glycylcyclines. Only DMG-DMDOT, ciprofloxacin, teicoplanin and vancomycin exhibited comparable activity against penicillin-susceptible, -intermediate and -resistant S. pneumoniae strains.

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Year:  1995        PMID： 8537270     DOI： 10.1093/jac/36.1.225

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  6 in total

Review 1.  Antibiotic resistance: a current perspective.

Authors:  K F Barker
Journal:  Br J Clin Pharmacol       Date:  1999-08       Impact factor: 4.335

2.  Antipneumococcal activities of GAR-936 (a new glycylcycline) compared to those of nine other agents against penicillin-susceptible and -resistant pneumococci.

Authors:  D B Hoellman; G A Pankuch; M R Jacobs; P C Appelbaum
Journal:  Antimicrob Agents Chemother       Date:  2000-04       Impact factor: 5.191

3.  Learning to live with MRSA.

Authors:  M Rahman
Journal:  Postgrad Med J       Date:  1998-07       Impact factor: 2.401

4.  Antibacterial agents that inhibit two-component signal transduction systems.

Authors:  J F Barrett; R M Goldschmidt; L E Lawrence; B Foleno; R Chen; J P Demers; S Johnson; R Kanojia; J Fernandez; J Bernstein; L Licata; A Donetz; S Huang; D J Hlasta; M J Macielag; K Ohemeng; R Frechette; M B Frosco; D H Klaubert; J M Whiteley; L Wang; J A Hoch
Journal:  Proc Natl Acad Sci U S A       Date:  1998-04-28       Impact factor: 11.205

5.  Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance.

Authors:  I Chopra; M Roberts
Journal:  Microbiol Mol Biol Rev       Date:  2001-06       Impact factor: 11.056

6.  The management of infection and colonization due to methicillin-resistant Staphylococcus aureus: A CIDS/CAMM position paper.

Authors:  Andrew E Simor; Mark Loeb
Journal:  Can J Infect Dis       Date:  2004-01
  6 in total

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