Literature DB >> 8535927

Cytochromes P450 and drug toxicity. Immunological consequences.

D Mansuy1.   

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Year:  1995        PMID： 8535927     DOI： 10.1007/BF02771761

Source DB:  PubMed          Journal:  Clin Rev Allergy Immunol        ISSN： 1080-0549            Impact factor:   8.667


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  10 in total

Review 1.  Autoantibodies against cytochromes P450: role in human diseases.

Authors:  P Beaune; D Pessayre; P Dansette; D Mansuy; M Manns
Journal:  Adv Pharmacol       Date:  1994

2.  Metabolic hydroxylation of the thiophene ring: isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and rat.

Authors:  D Mansuy; P M Dansette; C Foures; M Jaouen; G Moinet; N Bayer
Journal:  Biochem Pharmacol       Date:  1984-05-01       Impact factor: 5.858

3.  Ticrynafen-associated hepatic injury: analysis of 340 cases.

Authors:  H J Zimmerman; J H Lewis; K G Ishak; W C Maddrey
Journal:  Hepatology       Date:  1984 Mar-Apr       Impact factor: 17.425

4.  Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug.

Authors:  P Beaune; P M Dansette; D Mansuy; L Kiffel; M Finck; C Amar; J P Leroux; J C Homberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

5.  Human-liver cytochromes P-450 expressed in yeast as tools for reactive-metabolite formation studies. Oxidative activation of tienilic acid by cytochromes P-450 2C9 and 2C10.

Authors:  M P Lopez Garcia; P M Dansette; P Valadon; C Amar; P H Beaune; F P Guengerich; D Mansuy
Journal:  Eur J Biochem       Date:  1993-04-01

6.  Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid.

Authors:  M P López-Garcia; P M Dansette; D Mansuy
Journal:  Biochemistry       Date:  1994-01-11       Impact factor: 3.162

7.  Evidence for thiophene-S-oxide as a primary reactive metabolite of thiophene in vivo: formation of a dihydrothiophene sulfoxide mercapturic acid.

Authors:  P M Dansette; D C Thang; H el Amri; D Mansuy
Journal:  Biochem Biophys Res Commun       Date:  1992-08-14       Impact factor: 3.575

8.  Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodies.

Authors:  J C Homberg; N Abuaf; S Helmy-Khalil; M Biour; R Poupon; S Islam; F Darnis; V G Levy; P Opolon; M Beaugrand
Journal:  Hepatology       Date:  1985 Sep-Oct       Impact factor: 17.425

9.  Specificity of in vitro covalent binding of tienilic acid metabolites to human liver microsomes in relationship to the type of hepatotoxicity: comparison with two directly hepatotoxic drugs.

Authors:  S Lecoeur; E Bonierbale; D Challine; J C Gautier; P Valadon; P M Dansette; R Catinot; F Ballet; D Mansuy; P H Beaune
Journal:  Chem Res Toxicol       Date:  1994 May-Jun       Impact factor: 3.739

10.  Hydroxylation and formation of electrophilic metabolites of tienilic acid and its isomer by human liver microsomes. Catalysis by a cytochrome P450 IIC different from that responsible for mephenytoin hydroxylation.

Authors:  P M Dansette; C Amar; P Valadon; C Pons; P H Beaune; D Mansuy
Journal:  Biochem Pharmacol       Date:  1991-02-15       Impact factor: 5.858
  10 in total

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