Literature DB >> 8534402

Antibacterial phloroglucinols and flavonoids from Hypericum brasiliense.

L Rocha1, A Marston, O Potterat, M A Kaplan, H Stoeckli-Evans, K Hostettmann.   

Abstract

Three known phloroglucinols (japonicine A, uliginosin A and isouliginosin B) and a new phloroglucinol (hyperbrasiol A) have been isolated from a petrol extract of the leaves and flowers of Hypericum brasiliense. Their structures were established by spectroscopic methods (UV, DCI-MS, 1H and 13CNMR, including SINEPT, HMBC, HSQC, DQFCOSY experiments). The substitution pattern of hyperbrasilol A was confirmed by X-ray crystallography. All four phloroglucinols were antibacterial against Bacillus subtilis in a TLC bioautographic assay. The flavonoids, kaempferol, luteolin, quercetin, quercitrin, isoquercitrin, hyperoside and guaijaverin, were isolated from a methanol extract of the same organs.

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Year:  1995        PMID: 8534402     DOI: 10.1016/0031-9422(95)00507-4

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  13 in total

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4.  Identification and biosynthesis of acylphloroglucinols in Hypericum gentianoides.

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6.  Hypericum brasiliense plant extract neutralizes some biological effects of Bothrops jararaca snake venom.

Authors:  Mariane Assafim; Eduardo Coriolano de Coriolano; Sérgio Eufrázio Benedito; Caio Pinho Fernandes; Jonathas Felipe Revoredo Lobo; Eladio Florez Sanchez; Leandro Machado Rocha; André Lopes Fuly
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Review 8.  Bioautography and its scope in the field of natural product chemistry.

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9.  Chemical Composition and New Biological Activities of Essential Oil and Hydrosol of Hypericum perforatum L. ssp. veronense (Schrank) H. Lindb.

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Journal:  Plants (Basel)       Date:  2021-05-19

Review 10.  Detection progress of selected drugs in TLC.

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Journal:  Biomed Res Int       Date:  2014-01-16       Impact factor: 3.411

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