Literature DB >> 8532259

Electroejaculation and assisted reproductive techniques for anejaculatory infertility.

P H Chung1, B S Verkauf, R D Eichberg, L Casady, E J Sanford, G B Maroulis.   

Abstract

OBJECTIVE: To report our experience with electroejaculation combined with intrauterine inseminations (IUI) and other assisted reproductive technologies.
METHODS: Anejaculatory men desirous of fertility were evaluated in our Assisted Reproductive Program. Between March 1991 and December 1994, 26 men (age 24-48) underwent a total of 84 electroejaculations. Causes of anejaculation included spinal cord injury (n = 23) and retroperitoneal lymph node dissection (n = 3). Female partners were super-ovulated to improve the pregnancy rate. The success in sperm retrieval and pregnancy rates were determined, and the quality of electroejaculates was evaluated.
RESULTS: Seventy-seven of 84 (92%) electroejaculations were successful, defined by retrieval of more than 10 x 10(6) total and more than 10(6) motile spermatozoa. Mean sperm count was 65 million/mL (range 0-569), but mean motility was only 16% (range 0-66). Mean normal morphology was 27% (range 0-71). Ten couples attempted conception. Fifty cycles of IUIs were performed, resulting in four normal term infants and one spontaneous abortion (pregnancy rate 10% per IUI). One patient failed to conceive with eight cycles of IUIs but became pregnant with in vitro fertilization-embryo transfer with micromanipulation using electroejaculates; she delivered a set of healthy twins. Two couples elected donor sperm insemination after failing to conceive by IUI with electroejaculates; both became pregnant.
CONCLUSION: Electroejaculation offers an encouraging pregnancy opportunity for anejaculatory men who otherwise are considered infertile. Marked asthenospermia is observed in electroejaculates, the etiology of which remains obscure. Further studies to elucidate the cause may improve pregnancy rates.

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Year:  1996        PMID: 8532259     DOI: 10.1016/0029-7844(95)00335-5

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  4 in total

1.  Early spermatogenesis changes in traumatic complete spinal cord-injured adult patients.

Authors:  A Sánchez-Ramos; E Vargas-Baquero; F J Martin-de Francisco; J A Godino-Durán; I Rodriguez-Carrión; M Ortega-Ortega; L Mordillo-Mateos; F Coperchini; M Rotondi; A Oliviero; M Mas
Journal:  Spinal Cord       Date:  2017-01-24       Impact factor: 2.772

2.  Lipid Peroxidation and Its Role in the Expression of NLRP1a and NLRP3 Genes in Testicular Tissue of Male Rats: a Model of Spinal Cord Injury

Authors:  Mahshid Bazrafkan; Banafsheh Nikmehr; Abdolhossein Shahverdi; Fatemeh Hassani; Mahnaz Poorhassan; Tahmineh Mokhtari; Farid Abolhassani; Hamid Choobineh; Cordian Beyer; Gholamreza Hassanzadeh
Journal:  Iran Biomed J       Date:  2017-10-16

Review 3.  Infertility in men with spinal cord injury: research and treatment.

Authors:  Nancy L Brackett
Journal:  Scientifica (Cairo)       Date:  2012-11-25

Review 4.  Male Sexual Dysfunctions in the Infertile Couple-Recommendations From the European Society of Sexual Medicine (ESSM).

Authors:  Paolo Capogrosso; Christian Fuglesang S Jensen; Giulia Rastrelli; Josep Torremade; Giorgio I Russo; Amr Abdel Raheem; Anders Frey; Mikkel Fode; Mario Maggi; Yacov Reisman; Carlo Bettocchi; Giovanni Corona
Journal:  Sex Med       Date:  2021-06-02       Impact factor: 2.491

  4 in total

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