| Literature DB >> 8531836 |
Abstract
Chronically activated macrophages and T-lymphocytes, along with excessive interleukin-2 and other cytokine secretions, were previously proposed as the fundamental mediators of schizophrenia. This paper provides further support for the immune model of schizophrenia, including evidence on neurotransmitter abnormalities, the low amplitude of the auditory P300 event-related potential, the neurodevelopmental model of schizophrenia and the possible involvement of the locus ceruleus in schizophrenia.Entities:
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Year: 1995 PMID: 8531836 DOI: 10.1016/0306-9877(95)90062-4
Source DB: PubMed Journal: Med Hypotheses ISSN: 0306-9877 Impact factor: 1.538