Literature DB >> 8530040

Identification of a novel conserved human gene, TEGT.

L Walter1, P Marynen, J Szpirer, G Levan, E Günther.   

Abstract

A novel gene, TEGT (testis enhanced gene transcript), has been identified in humans. It does not belong to any known gene family of vertebrates. The deduced amino acid sequence of the gene and a bacterial protein of unknown function show low but significant homology and very similar hydrophobicity profiles. Two different transcripts of TEGT occur, which are due to alternative usage of two polyadenylation sites. The presence of a nuclear targeting motif indicates that the gene product might localize to the nucleus. The TEGT gene maps to human chromosome 12q12-q13 and belongs to a syntenic group, which is conserved in human, mouse, and rat.

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Year:  1995        PMID： 8530040     DOI： 10.1006/geno.1995.1145

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  11 in total

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Review 4.  BAX inhibitor-1: between stress and survival.

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Authors:  M Kawai-Yamada; L Jin; K Yoshinaga; A Hirata; H Uchimiya
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6.  Camelpox, an emerging orthopox viral disease.

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7.  Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells.

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Journal:  Am J Pathol       Date:  2003-08       Impact factor: 4.307

8.  Yeast Bax inhibitor, Bxi1p, is an ER-localized protein that links the unfolded protein response and programmed cell death in Saccharomyces cerevisiae.

Authors:  James Cebulski; Joshua Malouin; Nathan Pinches; Vincent Cascio; Nicanor Austriaco
Journal:  PLoS One       Date:  2011-06-06       Impact factor: 3.240

9.  Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family.

Authors:  Guia Carrara; Nuno Saraiva; Caroline Gubser; Benjamin F Johnson; Geoffrey L Smith
Journal:  J Biol Chem       Date:  2012-03-14       Impact factor: 5.157

10.  A new inhibitor of apoptosis from vaccinia virus and eukaryotes.

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Journal:  PLoS Pathog       Date:  2007-02       Impact factor: 6.823
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