Literature DB >> 853001

Effect of biguanide treatment in obese children.

A Lütjens, J L Smit.   

Abstract

In seven children of normal weight and in nine obese children (more than 30% overweight) from 8 to 14 years of age, blood glucose and insulin levels were estimated. The obese children were then treated with dimethylbiguanide (Metformin-HCl) during 3 months. After this period the tests were repeated. It is shown that a significant reduction of the insulin values, insulinogen indices and weight occurred after this treatment.

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Year:  1977        PMID： 853001

Source DB:  PubMed          Journal:  Helv Paediatr Acta        ISSN： 0018-022X


  6 in total

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2.  A longitudinal study of serum insulin and insulin resistance as predictors of weight and body fat gain in African American and Caucasian children.

Authors:  N M Sedaka; C H Olsen; L E Yannai; W E Stutzman; A J Krause; R Sherafat-Kazemzadeh; T A Condarco; S M Brady; A P Demidowich; J C Reynolds; S Z Yanovski; V S Hubbard; J A Yanovski
Journal:  Int J Obes (Lond)       Date:  2016-08-18       Impact factor: 5.095

3.  Insulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese children.

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Journal:  J Pediatr       Date:  2006-01       Impact factor: 4.406

4.  Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial.

Authors:  Jack A Yanovski; Jonathan Krakoff; Christine G Salaita; Jennifer R McDuffie; Merel Kozlosky; Nancy G Sebring; James C Reynolds; Sheila M Brady; Karim A Calis
Journal:  Diabetes       Date:  2011-01-12       Impact factor: 9.461

5.  Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.

Authors:  Dennis M Styne; Silva A Arslanian; Ellen L Connor; Ismaa Sadaf Farooqi; M Hassan Murad; Janet H Silverstein; Jack A Yanovski
Journal:  J Clin Endocrinol Metab       Date:  2017-03-01       Impact factor: 5.958

6.  Pharmacological treatment of obesity in children and adolescents: present and future.

Authors:  Lorenzo Iughetti; Mariachiara China; Rossella Berri; Barbara Predieri
Journal:  J Obes       Date:  2010-12-15
  6 in total

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