Literature DB >> 8529577

Are environmental sentinels signaling?

G A LeBlanc1.   

Abstract

There is an increasing perception that environmental contamination by chemicals no longer poses a significant health threat and that relaxation of environmental regulations is warranted. However, many wildlife populations are showing signs of developmental, behavioral, and reproductive dysfunction due to environmental contamination by endocrine-disrupting chemicals. Scientists, regulators, and legislators must mobilize to identify current health threats posed by environmental pollutants, develop testing protocols that will detect such properties of new chemicals, and strengthen legislation designed to protect environmental health.

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Year:  1995        PMID: 8529577      PMCID: PMC1519157          DOI: 10.1289/ehp.95103888

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  23 in total

1.  Treatment of fish with hormones: solubilization and direct administration of steroids into aquaria water using acetone as a carrier solvent.

Authors:  R N Hunsinger; W M Howell
Journal:  Bull Environ Contam Toxicol       Date:  1991-08       Impact factor: 2.151

2.  Neonatal chlordecone exposure alters behavioral sex differentiation in female hamsters.

Authors:  L E Gray
Journal:  Neurotoxicology       Date:  1982-10       Impact factor: 4.294

3.  Kepone, mirex, dieldrin, and aldrin: estrogenic activity and the induction of persistent vaginal estrus and anovulation in rats following neonatal treatment.

Authors:  R J Gellert
Journal:  Environ Res       Date:  1978-07       Impact factor: 6.498

4.  DDT-induced feminization of gull embryos.

Authors:  D M Fry; C K Toone
Journal:  Science       Date:  1981-08-21       Impact factor: 47.728

Review 5.  Sexual differentiation in litter-bearing mammals: influence of sex of adjacent fetuses in utero.

Authors:  F S vom Saal
Journal:  J Anim Sci       Date:  1989-07       Impact factor: 3.159

6.  The effects of chlordane exposure during pre- and postnatal periods at environmentally relevant levels on sex steroid-mediated behaviors and functions in the rat.

Authors:  R A Cassidy; C V Vorhees; D J Minnema; L Hastings
Journal:  Toxicol Appl Pharmacol       Date:  1994-06       Impact factor: 4.219

7.  Ketoconazole blocks testosterone synthesis.

Authors:  A Pont; P L Williams; S Azhar; R E Reitz; C Bochra; E R Smith; D A Stevens
Journal:  Arch Intern Med       Date:  1982-11

8.  Regional cerebral blood flow during hypoxia-ischemia in the immature rat: comparison of iodoantipyrine and iodoamphetamine as radioactive tracers.

Authors:  M Ringel; R M Bryan; R C Vannucci
Journal:  Brain Res Dev Brain Res       Date:  1991-04-24

9.  Induction, suppression and inhibition of multiple hepatic cytochrome P450 isozymes in the male rat and bobwhite quail (Colinus virginianus) by ergosterol biosynthesis inhibiting fungicides (EBIFs).

Authors:  M J Ronis; M Ingelman-Sundberg; T M Badger
Journal:  Biochem Pharmacol       Date:  1994-11-16       Impact factor: 5.858

10.  The price of progress: environmental health in Latin America.

Authors:  H Black
Journal:  Environ Health Perspect       Date:  1994-12       Impact factor: 9.031

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  6 in total

1.  Influence of chlorine substituents on rates of oxidation of chlorinated biphenyls by the biphenyl dioxygenase of Burkholderia sp. strain LB400.

Authors:  C M Arnett; J V Parales; J D Haddock
Journal:  Appl Environ Microbiol       Date:  2000-07       Impact factor: 4.792

Review 2.  Chronic toxicity of environmental contaminants: sentinels and biomarkers.

Authors:  G A LeBlanc; L J Bain
Journal:  Environ Health Perspect       Date:  1997-02       Impact factor: 9.031

Review 3.  Environmental endocrine disruption: an effects assessment and analysis.

Authors:  T M Crisp; E D Clegg; R L Cooper; W P Wood; D G Anderson; K P Baetcke; J L Hoffmann; M S Morrow; D J Rodier; J E Schaeffer; L W Touart; M G Zeeman; Y M Patel
Journal:  Environ Health Perspect       Date:  1998-02       Impact factor: 9.031

Review 4.  Invertebrates in testing of environmental chemicals: are they alternatives?

Authors:  L Lagadic; T Caquet
Journal:  Environ Health Perspect       Date:  1998-04       Impact factor: 9.031

5.  Assessing chemicals for estrogenic/hormone-disrupting properties: lessons from carcinogenicity assessment.

Authors:  J Ashby
Journal:  Environ Health Perspect       Date:  1996-02       Impact factor: 9.031

Review 6.  Predicting health effects of exposures to compounds with estrogenic activity: methodological issues.

Authors:  R Rudel
Journal:  Environ Health Perspect       Date:  1997-04       Impact factor: 9.031

  6 in total

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