Literature DB >> 8529189

Premature babies and pharmacology.

J Hamilton.   

Abstract

In his research on the action of various drugs in newborns, Dr. Jacob Aranda of the Centre for Perinatal and Developmental Pharmacology Research in Montreal draws upon his expertise in both neonatology and pharmacology. His work has led to the acceptance of caffeine as a standard treatment of apnea in premature infants, and his current studies of ibuprofen as a possible treatment of cerebral intraventricular hemorrhage, a serious problem in some premature babies, have yielded promising results. Other areas being tackled by Aranda and his colleagues include pain control for newborns and the elusive pathology of sudden infant death syndrome. By shedding more light on neonatal development and the principles of drug action in newborns, these research projects will help to improve the odds for many babies who suffer the setback of being born too soon.

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Year:  1995        PMID: 8529189      PMCID: PMC1488195     

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  10 in total

1.  The role of adenosine in the vascular adaptation of neonatal cerebral blood flow during hypotension.

Authors:  N Laudignon; K Beharry; E Farri; J V Aranda
Journal:  J Cereb Blood Flow Metab       Date:  1991-05       Impact factor: 6.200

2.  The effects of topical lidocaine on infant response to circumcision.

Authors:  D Mudge; J B Younger
Journal:  J Nurse Midwifery       Date:  1989 Nov-Dec

3.  Effects of prostaglandins and indomethacin on cerebral blood flow and cerebral oxygen consumption of conscious newborn piglets.

Authors:  S Chemtob; N Laudignon; K Beharry; J Rex; D Varma; L Wolfe; J V Aranda
Journal:  Dev Pharmacol Ther       Date:  1990

4.  Efficacy of caffeine in treatment of apnea in the low-birth-weight infant.

Authors:  J V Aranda; W Gorman; H Bergsteinsson; T Gunn
Journal:  J Pediatr       Date:  1977-03       Impact factor: 4.406

5.  Influence of adenosine on cerebral blood flow during hypoxic hypoxia in the newborn piglet.

Authors:  N Laudignon; E Farri; K Beharry; J Rex; J V Aranda
Journal:  J Appl Physiol (1985)       Date:  1990-04

6.  Prostanoids determine the range of cerebral blood flow autoregulation of newborn piglets.

Authors:  S Chemtob; K Beharry; J Rex; D R Varma; J V Aranda
Journal:  Stroke       Date:  1990-05       Impact factor: 7.914

7.  The role of prostanoids in neonatal cerebral blood flow autoregulation.

Authors:  J V Aranda; K Beharry; B Sasyniuk; S Chemtob
Journal:  J Lipid Mediat       Date:  1993 Mar-Apr

8.  Topical anesthesia during circumcision in newborn infants.

Authors:  F Benini; C C Johnston; D Faucher; J V Aranda
Journal:  JAMA       Date:  1993-08-18       Impact factor: 56.272

9.  Pharmacokinetic profile of caffeine in the premature newborn infant with apnea.

Authors:  J V Aranda; C E Cook; W Gorman; J M Collinge; P M Loughnan; E W Outerbridge; A Aldridge; A H Neims
Journal:  J Pediatr       Date:  1979-04       Impact factor: 4.406

10.  Metabolism of theophylline to caffeine in human fetal liver.

Authors:  J V Aranda; A T Louridas; B B Vitullo; P Thom; A Aldridge; R Haber
Journal:  Science       Date:  1979-12-14       Impact factor: 47.728

  10 in total

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