Literature DB >> 8528272

Cloning, sequencing and expression of NAT1 and NAT2 encoding genes from rapid and slow acetylator inbred rats.

M A Doll1, D W Hein.   

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Year:  1995        PMID: 8528272     DOI: 10.1097/00008571-199508000-00009

Source DB:  PubMed          Journal:  Pharmacogenetics        ISSN: 0960-314X


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  14 in total

1.  Identification and functional characterization of arylamine N-acetyltransferases in eubacteria: evidence for highly selective acetylation of 5-aminosalicylic acid.

Authors:  C Deloménie; S Fouix; S Longuemaux; N Brahimi; C Bizet; B Picard; E Denamur; J M Dupret
Journal:  J Bacteriol       Date:  2001-06       Impact factor: 3.490

2.  Homology modelling and structural analysis of human arylamine N-acetyltransferase NAT1: evidence for the conservation of a cysteine protease catalytic domain and an active-site loop.

Authors:  F Rodrigues-Lima; C Deloménie; G H Goodfellow; D M Grant; J M Dupret
Journal:  Biochem J       Date:  2001-06-01       Impact factor: 3.857

3.  Characterization of a hormone response element in the mouse N-acetyltransferase 2 (Nat2*) promoter.

Authors:  L Estrada-Rodgers; G N Levy; W W Weber
Journal:  Gene Expr       Date:  1998

4.  Computational and experimental analyses of mammalian arylamine N-acetyltransferase structure and function.

Authors:  Jason M Walraven; John O Trent; David W Hein
Journal:  Drug Metab Dispos       Date:  2007-03-19       Impact factor: 3.922

5.  Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2.

Authors:  Jason M Walraven; Mark A Doll; David W Hein
Journal:  J Pharmacol Exp Ther       Date:  2006-07-07       Impact factor: 4.030

6.  Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.

Authors:  Kristin J Metry; Jason R Neale; Jean Bendaly; Ned B Smith; William M Pierce; David W Hein
Journal:  Drug Metab Dispos       Date:  2009-08-10       Impact factor: 3.922

7.  4,4'-methylenedianiline-induced hepatotoxicity is modified by N-acetyltransferase 2 (NAT2) acetylator polymorphism in the rat.

Authors:  Xiaoyan Zhang; Jason C Lambert; Mark A Doll; Jason M Walraven; Gavin E Arteel; David W Hein
Journal:  J Pharmacol Exp Ther       Date:  2005-09-28       Impact factor: 4.030

8.  Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat.

Authors:  David W Hein; Jean Bendaly; Jason R Neale; Mark A Doll
Journal:  Drug Metab Dispos       Date:  2008-09-17       Impact factor: 3.922

9.  Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and Functional characterization of a novel rNat3*2 genetic variant.

Authors:  Jason M Walraven; David F Barker; Mark A Doll; David W Hein
Journal:  Toxicol Sci       Date:  2007-06-12       Impact factor: 4.849

10.  4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.

Authors:  Felicia A Jefferson; Gong H Xiao; David W Hein
Journal:  Toxicol Sci       Date:  2008-10-08       Impact factor: 4.849

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