OBJECTIVE: The authors tested the hypothesis that the regional distribution of cerebral vasculature is anomalous in schizophrenia. METHOD: Dynamic susceptibility contrast magnetic resonance imaging was used to evaluate cerebral blood volume in the right and left occipital cortex, basal ganglia, and cerebellum of 10 subjects with schizophrenia and 10 healthy comparison subjects. RESULTS: Cerebral blood volume was greater in the schizophrenic subjects in every region studied. CONCLUSIONS: The findings suggest an abnormality of the configuration of cerebral blood vessels in schizophrenia.
OBJECTIVE: The authors tested the hypothesis that the regional distribution of cerebral vasculature is anomalous in schizophrenia. METHOD: Dynamic susceptibility contrast magnetic resonance imaging was used to evaluate cerebral blood volume in the right and left occipital cortex, basal ganglia, and cerebellum of 10 subjects with schizophrenia and 10 healthy comparison subjects. RESULTS: Cerebral blood volume was greater in the schizophrenic subjects in every region studied. CONCLUSIONS: The findings suggest an abnormality of the configuration of cerebral blood vessels in schizophrenia.
Authors: Jun Hua; Allison S Brandt; SeungWook Lee; Nicholas I S Blair; Yuankui Wu; Su Lui; Jaymin Patel; Andreia V Faria; Issel Anne L Lim; Paul G Unschuld; James J Pekar; Peter C M van Zijl; Christopher A Ross; Russell L Margolis Journal: Schizophr Bull Date: 2017-05-01 Impact factor: 9.306
Authors: Anna R Docherty; T Bernard Bigdeli; Alexis C Edwards; Silviu Bacanu; Donghyung Lee; Michael C Neale; Brandon K Wormley; Dermot Walsh; F Anthony O'Neill; Brien P Riley; Kenneth S Kendler; Ayman H Fanous Journal: Schizophr Res Date: 2015-03-13 Impact factor: 4.939
Authors: Madeline H Meier; Idan Shalev; Terrie E Moffitt; Shitij Kapur; Richard S E Keefe; Tien Y Wong; Daniel W Belsky; HonaLee Harrington; Sean Hogan; Renate Houts; Avshalom Caspi; Richie Poulton Journal: Am J Psychiatry Date: 2013-12 Impact factor: 18.112