Literature DB >> 8525434

Prevention of DNA 5-methylcytosine reutilization in human cells.

J A Vilpo1, L M Vilpo.   

Abstract

DNA methylation is an important process contributing to transcriptional regulation in animal and plant cells. The well known reutilization of DNA nucleotide bases indicated that DNA degradation occurs in many cells and tissues. On the other hand, the reutilization of 5-methyl-2'-deoxycytidine monophosphate in the DNA synthesis would have deleterious effects on gene regulation. Recent molecular insights into the exclusion of exogenous 5-methylcytosine from DNA are the subject of this review.

Entities:  

Mesh:

Substances:

Year:  1995        PMID: 8525434     DOI: 10.1007/bf02255783

Source DB:  PubMed          Journal:  Somat Cell Mol Genet        ISSN: 0740-7750


  2 in total

1.  Nucleoside derivatives of 5-methylcytosine suppress 5-azacytidine-induced reactivation of a silent transgene in suspension-cultured tobacco cells.

Authors:  Kazutoshi Yamagishi; Yoshio Kikuta
Journal:  Plant Biotechnol (Tokyo)       Date:  2021-03-25       Impact factor: 1.133

2.  Evidence for gene silencing by endogenous DNA methylation.

Authors:  R Holliday; T Ho
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-21       Impact factor: 11.205

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.