Literature DB >> 852541

[Features of ethmozine metabolism].

Iu I Vikhliaev, V P Zherdev, A N Gritsenko, Z I Ermakova.   

Abstract

A study of the aethozine metabolism in the urine of rats detected 14 metabolites, a number of which was identified, namely: 2-aminophenothiazine, 2-acetylamide-phenothiazine, ethyl ether of phenothiazine-carbamine-2-acid, their sulphoxides and also aethmozine sulphoxide. Of the aethmozine biotransformation processes is characteristic formation in the organism of the animals of significant quantities of transformation products with complete degradation of the side chain.

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Year:  1977        PMID: 852541

Source DB:  PubMed          Journal:  Farmakol Toksikol        ISSN: 0014-8318


  1 in total

1.  Disposition of moracizine (ethmozine) in healthy subjects after oral administration of radiolabelled drug.

Authors:  D L Howrie; H J Pieniaszek; R N Fogoros; R P Juhl; W L Schary; C C Whitney; L W Dittert
Journal:  Eur J Clin Pharmacol       Date:  1987       Impact factor: 2.953

  1 in total

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