| Literature DB >> 8525139 |
Abstract
The hyperfiltration theory challenged the view that glomerular filtration rate is a fixed function as well as that there is a good correlation between GFR and renal parenchymal damage. Glomerular filtration rate is a dynamic parameter that is diet-dependent and can be altered by hemodynamic maneuvers. Therefore, it is not a good indicator of renal lesion. The renal reserve is an indicator of the workload per nephron and may be a useful parameter to assess the progression of renal disease in the presence of dietary or pharmacological intervention.Entities:
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Year: 1995 PMID: 8525139
Source DB: PubMed Journal: Semin Nephrol ISSN: 0270-9295 Impact factor: 5.299