The role of cerebral perfusion pressure as origin of brain edema in acute arterial hypertension.

In a series in 8 cats, cerebral perfusion pressure (CPP) was evaluated over a period of 5 min after production of an acute arterial hypertension. The mean percentual increase of blood pressure, CPP and ICP equalled 100%. the fact, that ICP does not play any role in acute hypertension, indicates that an abrupt elevation of filtration pressure within the capillaries must be the decisive factor leading to edema.