Literature DB >> 8523384

Two new culprits in cardiovascular disease: QT dispersion and aldosterone.

A D Struthers1.   

Abstract

Two new culprits have arisen in chronic heart failure (CHF). QT dispersion, which is the maximum QT interval minus the minimum QT interval in an ECG, may well predict sudden cardiac death. Aldosterone produces many harmful effects: magnesium loss, myocardial fibrosis, sympathetic activation, baroreflex dysfunction and ventricular arrhythmias. The RALES study is currently examining whether spironolactone improves mortality in CHF.

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Year:  1995        PMID: 8523384

Source DB:  PubMed          Journal:  J Hum Hypertens        ISSN: 0950-9240            Impact factor:   3.012


  3 in total

Review 1.  Drug abusers who die during arrest or in custody.

Authors:  S B Karch; B G Stephens
Journal:  J R Soc Med       Date:  1999-03       Impact factor: 5.344

Review 2.  Aldosterone and vascular damage.

Authors:  D Duprez; M De Buyzere; E R Rietzschel; D L Clement
Journal:  Curr Hypertens Rep       Date:  2000-06       Impact factor: 5.369

Review 3.  Spironolactone in congestive heart failure.

Authors:  J E Soberman; K T Weber
Journal:  Curr Hypertens Rep       Date:  2000-10       Impact factor: 5.369

  3 in total

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