Literature DB >> 8523325

Medical management of right dorsal colitis in 5 horses: a retrospective study (1987-1993).

N D Cohen1, G K Carter, R H Mealey, T S Taylor.   

Abstract

Right dorsal colitis in horses has been associated with administration of phenylbutazone. Although reports of right dorsal colitis in this species have described surgical treatment associated with a poor prognosis, we have had success treating this condition medically. This report describes 5 horses with right dorsal colitis confirmed during celiotomy that were initially managed medically. All horses had a history of intermittent abdominal pain; weight loss was noted in only 1 horse. The doses (2.0 to 4.6 mg/kg PO bid) and duration (5 to 30 days) of administration of phenylbutazone were not unusually high relative to those recommended (4.4 mg/kg PO bid). Hypoproteinemia and hypoalbuminemia were observed in all horses at the time of admission; packed cell volume was low in 4 horses, and hypocalcemia was also observed in 4 horses. Three of 5 horses (60%) appeared to respond to dietary management and discontinuation of administration of nonsteroidal anti-inflammatory drugs. Dietary management consisted of feeding pelleted feed, and restricting or eliminating roughage for a period of at least 3 months. Two horses developed strictures of the right dorsal colon. One horse that developed a colonic stricture, possibly because its owners did not comply with recommendations for management, was subsequently treated surgically. The remaining horse that developed a stricture of the right dorsal colon was euthanized. These data indicate that some horses with right dorsal colitis can be successfully managed with medical treatment.

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Year:  1995        PMID: 8523325     DOI: 10.1111/j.1939-1676.1995.tb01079.x

Source DB:  PubMed          Journal:  J Vet Intern Med        ISSN: 0891-6640            Impact factor:   3.333


  4 in total

1.  Right dorsal colitis in the horse: minireview and reports on three cases in Ireland.

Authors:  Noreen Galvin; Hugh Dillon; Frank McGovern
Journal:  Ir Vet J       Date:  2004-08-01       Impact factor: 2.146

2.  Right dorsal colon ultrasonography in normal adult ponies and miniature horses.

Authors:  Natalia Siwinska; Agnieszka Zak; Monika Baron; Marta Cylna; Hieronim Borowicz
Journal:  PLoS One       Date:  2017-10-24       Impact factor: 3.240

3.  The non-invasive exfoliated transcriptome (exfoliome) reflects the tissue-level transcriptome in a mouse model of NSAID enteropathy.

Authors:  Canaan M Whitfield-Cargile; Noah D Cohen; Kejun He; Ivan Ivanov; Jennifer S Goldsby; Ana Chamoun-Emanuelli; Brad R Weeks; Laurie A Davidson; Robert S Chapkin
Journal:  Sci Rep       Date:  2017-10-31       Impact factor: 4.379

4.  Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses.

Authors:  Canaan M Whitfield-Cargile; Michelle C Coleman; Noah D Cohen; Ana M Chamoun-Emanuelli; Cristobal Navas DeSolis; Taylor Tetrault; Ryan Sowinski; Amanda Bradbery; Mattea Much
Journal:  J Vet Intern Med       Date:  2021-03-03       Impact factor: 3.333

  4 in total

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