Literature DB >> 8522483

Topical treatment of early cutaneous T-cell lymphoma.

D L Ramsay1, J A Meller, H S Zackheim.   

Abstract

The two major topical treatment modalities for cutaneous T-cell lymphoma (CTCL) are mechlorethamine (nitrogen mustard) and topical carmustine (BCNU). Topical mechorethamine hydrochloride has been used since the late 1950s as therapy for CTCL. Topical BCNU solution is a highly effective treatment for early stage mycosis fungoides. This article describes these two modalities.

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Year:  1995        PMID： 8522483

Source DB:  PubMed          Journal:  Hematol Oncol Clin North Am        ISSN： 0889-8588            Impact factor:   3.722


  7 in total

1.  Successful Use of the 308-nm Excimer Laser in Early Patch Stage Mycosis Fungoides.

Authors:  Andrew M Armenta; Krystal M Jones; Jason S Reichenberg
Journal:  J Lasers Med Sci       Date:  2019-07-06

2.  Phase I clinical trial of O6-benzylguanine and topical carmustine in the treatment of cutaneous T-cell lymphoma, mycosis fungoides type.

Authors:  Narin Apisarnthanarax; Gary S Wood; Seth R Stevens; Sean Carlson; Derek V Chan; Lili Liu; Sarolta K Szabo; Pingfu Fu; Anita C Gilliam; Stanton L Gerson; Scot C Remick; Kevin D Cooper
Journal:  Arch Dermatol       Date:  2012-05

3.  Topical chemotherapy in cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis fungoides.

Authors:  Stuart R Lessin; Madeleine Duvic; Joan Guitart; Amit G Pandya; Bruce E Strober; Elise A Olsen; Christopher M Hull; Elizabeth H Knobler; Alain H Rook; Ellen J Kim; Mark F Naylor; David M Adelson; Alexa B Kimball; Gary S Wood; Uma Sundram; Hong Wu; Youn H Kim
Journal:  JAMA Dermatol       Date:  2013-01       Impact factor: 10.282

4.  Evaluation of T-cell receptor gene rearrangements in patients with recurrent patch/plaque (T2) CTCL (mycosis fungoides).

Authors:  M Thayu; G Tallini; E J Glusac; B M Kacinski; L D Wilson
Journal:  Yale J Biol Med       Date:  1999 Nov-Dec

5.  Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report.

Authors:  Xiaojuan Zhang; Zhidan Zhang; Song Chen; Dongmei Zhao; Fangxiao Zhang; Ziwei Hu; Feng Xiao; Xiaochun Ma
Journal:  Exp Ther Med       Date:  2015-07-29       Impact factor: 2.447

6.  The PROVe Study: US Real-World Experience with Chlormethine/Mechlorethamine Gel in Combination with Other Therapies for Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma.

Authors:  Ellen J Kim; Joan Guitart; Christiane Querfeld; Michael Girardi; Amy Musiek; Oleg E Akilov; James T Angello; William L Bailey; Larisa J Geskin
Journal:  Am J Clin Dermatol       Date:  2021-03-03       Impact factor: 7.403

7.  Chlormethine Gel in Combination with Other Therapies in the Treatment of Patients with Mycosis Fungoides Cutaneous T Cell Lymphoma: Three Case Reports.

Authors:  Kyriaki Lampadaki; Marios Koumourtzis; Fani Karagianni; Leonidas Marinos; Evangelia Papadavid
Journal:  Adv Ther       Date:  2021-04-30       Impact factor: 3.845
  7 in total

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