Literature DB >> 8522383

Serum TNF-alpha, sCD8 and sIL-2R levels in childhood tuberculosis.

I B Barlan1, M M Başaran, M Bakir, F Tükenmez, N Bekiroğlu.   

Abstract

In this study we have determined the serum tumor necrosis factor-alpha (TNF-alpha), soluble CD8 (sCD8) and soluble interleukin-2 receptor (sIL-2R) levels in children with active pulmonary tuberculosis (n = 66) and healthy controls (n = 20). Measurable serum TNF-alpha levels were detected in nine of 86 children (10.5%), all of whom belonged to the group with active disease. Serum sCD8 and sIL-2R determinations revealed a significant difference between the group with active pulmonary tuberculosis and the controls (p < 0.05). Deeper insight into the involvement of cytokines and T cells will provide a better understanding

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Year:  1995        PMID： 8522383     DOI： 10.1007/bf01781205

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  12 in total

1.  In vitro analysis of the cellular mechanisms involved in immunity to tuberculosis.

Authors:  S H Kaufmann
Journal:  Rev Infect Dis       Date:  1989 Mar-Apr

Review 2.  The role of cytokines in the immunopathology of tuberculosis, and the regulation of agalactosyl IgG.

Authors:  G A Rook; R A Attiyah; N Foley
Journal:  Lymphokine Res       Date:  1989

3.  Local production of tumor necrosis factor and IFN-gamma in tuberculous pleuritis.

Authors:  P F Barnes; S J Fong; P J Brennan; P E Twomey; A Mazumder; R L Modlin
Journal:  J Immunol       Date:  1990-07-01       Impact factor: 5.422

4.  Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria.

Authors:  M E Munk; A J Gatrill; S H Kaufmann
Journal:  J Immunol       Date:  1990-10-15       Impact factor: 5.422

5.  Interleukin-2 and soluble interleukin-2 receptor levels in children with active pulmonary tuberculosis and atypical mycobacterial adenitis.

Authors:  J Nyabenda; M Turneer; A Waelbroeck; A Duvivier; M Toppet
Journal:  Eur Cytokine Netw       Date:  1993 Jan-Feb       Impact factor: 2.737

6.  Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection.

Authors:  J L Flynn; M M Goldstein; K J Triebold; B Koller; B R Bloom
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

7.  Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex.

Authors:  L E Bermudez; L S Young
Journal:  J Immunol       Date:  1988-05-01       Impact factor: 5.422

8.  Cachectin/tumor necrosis factor: production, distribution, and metabolic fate in vivo.

Authors:  B A Beutler; I W Milsark; A Cerami
Journal:  J Immunol       Date:  1985-12       Impact factor: 5.422

9.  Raised serum levels of tumour necrosis factor in parasitic infections.

Authors:  P Scuderi; K E Sterling; K S Lam; P R Finley; K J Ryan; C G Ray; E Petersen; D J Slymen; S E Salmon
Journal:  Lancet       Date:  1986-12-13       Impact factor: 79.321

10.  In vivo depletion of CD4 and CD8 T lymphocytes impairs Mycobacterium w vaccine-induced protection against M. tuberculosis in mice.

Authors:  I Guleria; R Mukherjee; S H Kaufmann
Journal:  Med Microbiol Immunol       Date:  1993-07       Impact factor: 3.402
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