Literature DB >> 8520888

Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis.

V Deretic1, M J Schurr, H Yu.   

Abstract

During chronic infections in cystic fibrosis, persistence of Pseudomonas aeruginosa is associated with conversion into forms that are associated with conversion into forms that are characterized by a mucoid colony morphology, rough lipopolysaccharide and, paradoxically, decreased systemic virulence. The mutations underlying these changes occur in global regulators, such as alternative sigma factors and their accessory elements.

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Year:  1995        PMID： 8520888     DOI： 10.1016/s0966-842x(00)88974-x

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  48 in total

1.  Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence.

Authors:  N P West; H Jungnitz; J T Fitter; J D McArthur; C A Guzmán; M J Walker
Journal:  Infect Immun       Date:  2000-08       Impact factor: 3.441

2.  A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria.

Authors:  Rachel D Hood; Pragya Singh; Fosheng Hsu; Tüzün Güvener; Mike A Carl; Rex R S Trinidad; Julie M Silverman; Brooks B Ohlson; Kevin G Hicks; Rachael L Plemel; Mo Li; Sandra Schwarz; Wenzhuo Y Wang; Alexey J Merz; David R Goodlett; Joseph D Mougous
Journal:  Cell Host Microbe       Date:  2010-01-21       Impact factor: 21.023

3.  Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE).

Authors:  H Yu; J C Boucher; N S Hibler; V Deretic
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

4.  Determination of the regulon and identification of novel mRNA targets of Pseudomonas aeruginosa RsmA.

Authors:  Anja Brencic; Stephen Lory
Journal:  Mol Microbiol       Date:  2009-05       Impact factor: 3.501

5.  Global genomic analysis of AlgU (sigma(E))-dependent promoters (sigmulon) in Pseudomonas aeruginosa and implications for inflammatory processes in cystic fibrosis.

Authors:  Aaron M Firoved; J Cliff Boucher; Vojo Deretic
Journal:  J Bacteriol       Date:  2002-02       Impact factor: 3.490

6.  The alternative sigma factor AlgT represses Pseudomonas aeruginosa flagellum biosynthesis by inhibiting expression of fleQ.

Authors:  Anne H Tart; Matthew C Wolfgang; Daniel J Wozniak
Journal:  J Bacteriol       Date:  2005-12       Impact factor: 3.490

Review 7.  Clinical significance of microbial infection and adaptation in cystic fibrosis.

Authors:  Alan R Hauser; Manu Jain; Maskit Bar-Meir; Susanna A McColley
Journal:  Clin Microbiol Rev       Date:  2011-01       Impact factor: 26.132

8.  Recovery of birth weight z score within 2 years of diagnosis is positively associated with pulmonary status at 6 years of age in children with cystic fibrosis.

Authors:  Huichuan J Lai; Suzanne M Shoff; Philip M Farrell
Journal:  Pediatrics       Date:  2009-02       Impact factor: 7.124

9.  Cif is negatively regulated by the TetR family repressor CifR.

Authors:  Daniel P MacEachran; Bruce A Stanton; George A O'Toole
Journal:  Infect Immun       Date:  2008-05-05       Impact factor: 3.441

10.  Burkholderia type VI secretion systems have distinct roles in eukaryotic and bacterial cell interactions.

Authors:  Sandra Schwarz; T Eoin West; Frédéric Boyer; Wen-Chi Chiang; Mike A Carl; Rachel D Hood; Laurence Rohmer; Tim Tolker-Nielsen; Shawn J Skerrett; Joseph D Mougous
Journal:  PLoS Pathog       Date:  2010-08-26       Impact factor: 6.823
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