Literature DB >> 8520881

Have enteric infections a role in 5-fluorouracil-associated diarrhea?

S Cascinu1, G Catalano.   

Abstract

In 16 advanced colorectal cancer patients with 5-fluorouracil-associated diarrhea, we evaluated the role of bacterial pathogens in the development of this adverse effect. Neither Clostridium difficile nor other pathogens were cultured from fecal specimens. These data seem to suggest that it is unlikely that intestinal infections have a role in the pathogenesis of 5FU-associated diarrhea.

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Year:  1995        PMID： 8520881     DOI： 10.1007/bf00335311

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN： 0941-4355            Impact factor:   3.603


  9 in total

Review 1.  Drug therapy in diarrheal diseases in oncology/hematology patients.

Authors:  S Cascinu
Journal:  Crit Rev Oncol Hematol       Date:  1995-01       Impact factor: 6.312

2.  Severe and fatal toxic effects observed in treatment with high- and low-dose leucovorin plus 5-fluorouracil for colorectal carcinoma.

Authors:  J L Grem; D D Shoemaker; N J Petrelli; H O Douglass
Journal:  Cancer Treat Rep       Date:  1987-11

3.  Clinical update on the role of fluorouracil and recombinant interferon alfa-2a in the treatment of colorectal carcinoma.

Authors:  S Wadler; P H Wiernik
Journal:  Semin Oncol       Date:  1990-02       Impact factor: 4.929

4.  Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients.

Authors:  M Tvede; J Rask-Madsen
Journal:  Lancet       Date:  1989-05-27       Impact factor: 79.321

5.  Clostridium difficile colitis associated with the use of antineoplastic agents.

Authors:  S D Miller; H J Koornhof
Journal:  Eur J Clin Microbiol       Date:  1984-02       Impact factor: 3.267

6.  Commercial latex agglutination test for detection of Clostridium difficile-associated diarrhea.

Authors:  M T Kelly; S G Champagne; C H Sherlock; M A Noble; H J Freeman; J A Smith
Journal:  J Clin Microbiol       Date:  1987-07       Impact factor: 5.948

7.  Morphometric analysis of the effects of antineoplastic drugs on mucosa of normal ileum and ileal anastomoses in rats.

Authors:  D B de Roy van Zuidewijn; P H Schillings; T Wobbes; T Hendriks; H H de Boer
Journal:  Exp Mol Pathol       Date:  1992-04       Impact factor: 3.362

8.  Clostridium difficile colitis associated with cancer chemotherapy.

Authors:  M A Cudmore; J Silva; R Fekety; M K Liepman; K H Kim
Journal:  Arch Intern Med       Date:  1982-02

9.  High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer.

Authors:  H Nielsen; G Daugaard; M Tvede; B Bruun
Journal:  Br J Cancer       Date:  1992-10       Impact factor: 7.640
  9 in total

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