| Literature DB >> 8519813 |
P Crepieux1, J Coll, D Stehelin.
Abstract
Members of the Ets family of transcriptional regulators play pivotal roles in physiological processes, such as embryonic development or immune response. The Ets family proteins possess unique regulatory features because they bind DNA as monomers and their respective activities rely more on their ability to interact with other transcription factors than on their specific binding to a cognate DNA sequence. This review focuses on such interactions and also explores dysregulated expression of the Ets proteins in human cancers.Entities:
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Year: 1994 PMID： 8519813
Source DB: PubMed Journal: Crit Rev Oncog ISSN： 0893-9675