| Literature DB >> 8519795 |
O Hill1, Y Cetin, A Cieslak, H J Mägert, W G Forssmann.
Abstract
We have amplified, cloned, and sequenced 583 bp GCAP-II/uroguanylin-specific cDNA from human colon cDNA first strand. The cDNA codes for a putative 112 amino-acid precursor protein including the sequence of uroguanylin and GCAP-II. Northern blot hybridization revealed a high level expression of the GCAP-II gene in human colon, but not in the kidney. This expression of GCAP-II indicates a pivotal role in cGMP-mediated functions of the colon.Entities:
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Year: 1995 PMID： 8519795 DOI： 10.1016/0167-4838(95)00204-4
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002