Literature DB >> 8518540

Coronary microcirculation in hypertensive heart disease: functional significance and therapeutic implications.

W Motz1, M Vogt, B E Strauer.   

Abstract

In arterial hypertension left ventricular hypertrophy comprises myocyte hypertrophy, interstitial fibrosis and structural alterations of the coronary microcirculation. This leads to an impairment of diastolic function of the left ventricle and coronary flow reserve despite normal epicardial arteries. Consequently, antihypertensive treatment should aim at [13] reversing myocyte hypertrophy, [14] restoring myocardial structure and [8] improving coronary flow reserve along with blood pressure normalization.

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Year:  1993        PMID: 8518540     DOI: 10.1007/BF00180075

Source DB:  PubMed          Journal:  Clin Investig        ISSN: 0941-0198


  16 in total

1.  Myocardial oxygen consumption in chronic heart disease: role of wall stress, hypertrophy and coronary reserve.

Authors:  B E Strauer
Journal:  Am J Cardiol       Date:  1979-10       Impact factor: 2.778

2.  The significance of coronary reserve in clinical heart disease.

Authors:  B E Strauer
Journal:  J Am Coll Cardiol       Date:  1990-03-15       Impact factor: 24.094

Review 3.  Coronary flow reserve in arterial hypertension.

Authors:  M Vogt; W Motz; B E Strauer
Journal:  Scand J Clin Lab Invest Suppl       Date:  1989

4.  Coronary circulation in arterial hypertension.

Authors:  W Motz; M Vogt; S Scheler; B Schwartzkopff; B E Strauer
Journal:  J Cardiovasc Pharmacol       Date:  1991       Impact factor: 3.105

Review 5.  Morphologic characteristics and functional significance of focal fibromuscular dysplasia of small coronary arteries.

Authors:  T N James
Journal:  Am J Cardiol       Date:  1990-04-03       Impact factor: 2.778

6.  Angina due to coronary microvascular disease in hypertensive patients without left ventricular hypertrophy.

Authors:  J E Brush; R O Cannon; W H Schenke; R O Bonow; M B Leon; B J Maron; S E Epstein
Journal:  N Engl J Med       Date:  1988-11-17       Impact factor: 91.245

7.  Morphometric investigation of human myocardium in arterial hypertension and valvular aortic stenosis.

Authors:  B Schwartzkopff; H Frenzel; J Dieckerhoff; P Betz; M Flasshove; H D Schulte; M Mundhenke; W Motz; B E Strauer
Journal:  Eur Heart J       Date:  1992-09       Impact factor: 29.983

8.  Cardioreparative effects of lisinopril in rats with genetic hypertension and left ventricular hypertrophy.

Authors:  C G Brilla; J S Janicki; K T Weber
Journal:  Circulation       Date:  1991-05       Impact factor: 29.690

9.  Morphometry of canine coronary arteries, arterioles, and capillaries during hypertension and left ventricular hypertrophy.

Authors:  R J Tomanek; P J Palmer; G L Peiffer; K L Schreiber; C L Eastham; M L Marcus
Journal:  Circ Res       Date:  1986-01       Impact factor: 17.367

Review 10.  Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

Authors:  K T Weber; C G Brilla
Journal:  Circulation       Date:  1991-06       Impact factor: 29.690

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  1 in total

Review 1.  What is the current status of quantification and nuclear medicine in cardiology?

Authors:  G Hör
Journal:  Eur J Nucl Med       Date:  1996-07
  1 in total

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