| Literature DB >> 8518455 |
Abstract
The structure of the glucose transporter and the characteristics of the identified members of the facilitative glucose transporter gene family (GLUT1-5) are reviewed. The role of glucose transport in insulin resistance and non-insulin-dependent diabetes mellitus (NIDDM) is discussed. The potential contributions of genetic mutation and disruption of short- or long-term regulation of glucose transporters, particularly GLUT4, in insulin-sensitive tissues to the etiology of NIDDM are examined.Entities:
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Year: 1993 PMID： 8518455 DOI： 10.1016/1056-8727(93)90038-z
Source DB: PubMed Journal: J Diabetes Complications ISSN： 1056-8727 Impact factor: 2.852