OBJECTIVES: To assess the incidence and significance of anticardiolipin antibodies after myocardial infarction and in unstable angina. DESIGN: A prospective study of all patients under 60 admitted to the coronary care unit over a 12 month period with a diagnosis of acute myocardial infarction who were followed up for a further 12 months. Patients admitted with unstable angina were similarly assessed but not followed up. Anticardiolipin antibody concentrations were compared with those of age matched controls. SETTING: A district general hospital. PATIENTS: 307 patients with acute myocardial infarction and 160 patients with unstable angina. RESULTS: Anticardiolipin antibody concentrations in the two patient groups did not differ significantly from those in the control groups. Antibody concentrations were not related to a history of angina or myocardial infarction nor were they related to subsequent cardiovascular complications. CONCLUSION: This study shows no significant association between anticardiolipin antibody concentrations and either myocardial infarction or unstable angina.
OBJECTIVES: To assess the incidence and significance of anticardiolipin antibodies after myocardial infarction and in unstable angina. DESIGN: A prospective study of all patients under 60 admitted to the coronary care unit over a 12 month period with a diagnosis of acute myocardial infarction who were followed up for a further 12 months. Patients admitted with unstable angina were similarly assessed but not followed up. Anticardiolipin antibody concentrations were compared with those of age matched controls. SETTING: A district general hospital. PATIENTS: 307 patients with acute myocardial infarction and 160 patients with unstable angina. RESULTS: Anticardiolipin antibody concentrations in the two patient groups did not differ significantly from those in the control groups. Antibody concentrations were not related to a history of angina or myocardial infarction nor were they related to subsequent cardiovascular complications. CONCLUSION: This study shows no significant association between anticardiolipin antibody concentrations and either myocardial infarction or unstable angina.
Authors: P L Meroni; E N Harris; A Brucato; A Tincani; W Barcellini; A Vismara; G Balestrieri; G R Hughes; C Zanussi Journal: Clin Exp Immunol Date: 1987-03 Impact factor: 4.330
Authors: K E Morton; T P Gavaghan; S A Krilis; G E Daggard; D W Baron; J B Hickie; C N Chesterman Journal: Lancet Date: 1986-12-13 Impact factor: 79.321
Authors: A Doria; Y Shoenfeld; R Wu; P F Gambari; M Puato; A Ghirardello; B Gilburd; S Corbanese; M Patnaik; S Zampieri; J B Peter; E Favaretto; L Iaccarino; Y Sherer; S Todesco; P Pauletto Journal: Ann Rheum Dis Date: 2003-11 Impact factor: 19.103