Literature DB >> 8516975

Pancreatic polypeptide and exocrine pancreatic function in the elderly.

F I al-Modaris1, I C Taylor, J G McConnell, M J Power, E Armstrong, K D Buchanan.   

Abstract

The relationship between exocrine pancreatic function and plasma pancreatic polypeptide levels was studied in 14 normal elderly subjects and in ten elderly patients with exocrine pancreatic insufficiency determined by the para-amino-benzoic acid test. There was a decrease in the total pancreatic polypeptide response after a standard mixed meal in the group with pancreatic insufficiency (t = 2.753, p = 0.01). An increase above basal of less than 100% in plasma pancreatic polypeptide levels 30 min after a standard mixed meal is strongly associated with exocrine pancreatic insufficiency (Fisher's exact test, p = 0.005).

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Year:  1993        PMID: 8516975      PMCID: PMC2449007     

Source DB:  PubMed          Journal:  Ulster Med J        ISSN: 0041-6193


  18 in total

Review 1.  Radioimmunoassay of GI hormones.

Authors:  J Ardill
Journal:  Clin Endocrinol Metab       Date:  1979-07

2.  Release of pancreatic polypeptide in humans by infusion of cholecystokinin.

Authors:  J Lonovics; S Guzman; P Devitt; K E Hejtmancik; R L Suddith; P L Rayford; J C Thompson
Journal:  Gastroenterology       Date:  1980-11       Impact factor: 22.682

3.  Reduction of postprandial release of pancreatic polypeptide after development of pancreatic fibrosis.

Authors:  K Inoue; I Wiener; W K Gourley; L C Watson; P L Rayford; J C Thompson
Journal:  Surg Gynecol Obstet       Date:  1982-05

4.  Improved diagnostic accuracy of a modified oral pancreatic function test.

Authors:  C J Mitchell; C S Humphrey; A W Bullen; J Kelleher; M S Losowsky
Journal:  Scand J Gastroenterol       Date:  1979       Impact factor: 2.423

5.  Evidence for pyloropancreatic reflux for pancreatic exocrine secretion.

Authors:  H T Debas; T Yamagishi
Journal:  Am J Physiol       Date:  1978-05

6.  Pancreozymin bioassay in man based on pancreatic enzyme secretion: potency of specific amino acids and other digestive products.

Authors:  V L Go; A F Hofmann; W H Summerskill
Journal:  J Clin Invest       Date:  1970-08       Impact factor: 14.808

7.  Control of pancreatic polypeptide secretion by glucose in man.

Authors:  J Marco; J A Hedo; M L Villanueva
Journal:  J Clin Endocrinol Metab       Date:  1978-01       Impact factor: 5.958

8.  Pancreatic polypeptide response in patients with chronic pancreatitis.

Authors:  J E Valenzuela; I L Taylor; J H Walsh
Journal:  Dig Dis Sci       Date:  1979-11       Impact factor: 3.199

9.  Exocrine pancreatic insufficiency in presumed healthy elderly subjects.

Authors:  F I al-Modaris; M J Power; J G McConnell; I C Taylor; E Armstrong; K D Buchanan
Journal:  Age Ageing       Date:  1992-07       Impact factor: 10.668

10.  Correlation between exocrine pancreatic secretion and serum concentration of human pancreatic polypeptide in chronic pancreatitis.

Authors:  B N Andersen; C Hagen; H C Klein; F Stadil; H Worning
Journal:  Scand J Gastroenterol       Date:  1980       Impact factor: 2.423

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