Literature DB >> 8516782

Influence of chronic intoxication with selenium on collagen and elastin content in tissues of rat.

E J Kucharz1, K Olczyk.   

Abstract

Rats were intoxicated with sodium selenite (0.3 mg/kg body wt.) for 10 weeks. An increase in total collagen content in skin and a decrease in the lungs, liver and kidneys were observed. Enhanced serum and urine levels of collagen metabolites were found. Elastin content was shown to be increased in the lung, liver, heart muscle and kidney of selenium-intoxicated rats.

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Year:  1993        PMID： 8516782     DOI： 10.1016/0378-4274(93)90020-x

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  4 in total

1.  Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance.

Authors:  Nicole Metes-Kosik; Ivan Luptak; Patricia M Dibello; Diane E Handy; Shiow-Shih Tang; Hui Zhi; Fuzhong Qin; Donald W Jacobsen; Joseph Loscalzo; Jacob Joseph
Journal:  Mol Nutr Food Res       Date:  2012-10-24       Impact factor: 5.914

Review 2.  Selenistasis: epistatic effects of selenium on cardiovascular phenotype.

Authors:  Jacob Joseph; Joseph Loscalzo
Journal:  Nutrients       Date:  2013-01-31       Impact factor: 5.717

3.  Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents.

Authors:  Anna M Raines; Roger A Sunde
Journal:  BMC Genomics       Date:  2011-01-12       Impact factor: 3.969

4.  Toxic-selenium and low-selenium transcriptomes in Caenorhabditis elegans: toxic selenium up-regulates oxidoreductase and down-regulates cuticle-associated genes.

Authors:  Christopher J Boehler; Anna M Raines; Roger A Sunde
Journal:  PLoS One       Date:  2014-06-27       Impact factor: 3.240
  4 in total

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