Epidemiology of malignant melanoma, worldwide incidence, and etiologic factors.

Malignant melanoma is increasing at an alarming rate, exceeding that of any other cancer in the United States today. Genetic susceptibility and exposure to ultraviolet radiation are thought to be the two most important risk factors for development of the neoplasm. While genetic factors cannot be altered, minimizing exposure to ultraviolet light, especially intermittent intense type, and photoprotective measures may significantly reduce the development of this ominous cutaneous malignancy.