| Literature DB >> 8516377 |
L D Melville1, G P Smith, J Gibbs.
Abstract
We investigated the satiating potency of CCK-33 and of CCK-8 administered IP to rats prior to a 30-min food intake test using a high-carbohydrate liquid diet. CCK-33 and CCK-8 produced dose-related inhibitions of intake. The ID50S and the slopes of the dose-response functions of the two peptides were not significantly different. We conclude that CCK-33 is as potent as CCK-8 for inhibiting food intake in the rat.Entities:
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Year: 1993 PMID： 8516377 DOI： 10.1016/0091-3057(93)90090-g
Source DB: PubMed Journal: Pharmacol Biochem Behav ISSN： 0091-3057 Impact factor: 3.533