Literature DB >> 8516294

A motility in the eukaryotic flagellum unrelated to flagellar beating.

K G Kozminski1, K A Johnson, P Forscher, J L Rosenbaum.   

Abstract

We report a motility in the flagella of the green alga Chlamydomonas that is unrelated to dynein-based flagellar beating. This motility, referred to as intraflagellar transport, was observed as the rapid bidirectional movement of granule-like particles along the length of the flagella. Intraflagellar transport could be experimentally separated from other, previously reported, nonbeat flagellar motilities. EM of flagella showed groups of nonvesicular, lollipop-shaped structures positioned between the outer doublet microtubules and the flagellar membrane. Movement of these complexes along the length of the flagella may be responsible for intraflagellar transport.

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Year:  1993        PMID: 8516294      PMCID: PMC46752          DOI: 10.1073/pnas.90.12.5519

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  25 in total

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Authors:  G Piperno; D J Luck
Journal:  J Biol Chem       Date:  1979-04-25       Impact factor: 5.157

2.  Increased levels of mRNAs for tubulin and other flagellar proteins after amputation or shortening of Chlamydomonas flagella.

Authors:  P A Lefebvre; C D Silflow; E D Wieben; J L Rosenbaum
Journal:  Cell       Date:  1980-06       Impact factor: 41.582

Review 3.  Directed movements of ciliary and flagellar membrane components: a review.

Authors:  R A Bloodgood
Journal:  Biol Cell       Date:  1992       Impact factor: 4.458

4.  Flagellar regeneration in protozoan flagellates.

Authors:  J L Rosenbaum; F M Child
Journal:  J Cell Biol       Date:  1967-07       Impact factor: 10.539

5.  Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.

Authors:  P Forscher; S J Smith
Journal:  J Cell Biol       Date:  1988-10       Impact factor: 10.539

6.  Microtubule-membrane interactions in cilia. II. Photochemical cross-linking of bridge structures and the identification of a membrane-associated dynein-like ATPase.

Authors:  W L Dentler; M M Pratt; R E Stephens
Journal:  J Cell Biol       Date:  1980-02       Impact factor: 10.539

7.  Reversible inhibition of Chlamydomonas flagellar surface motility.

Authors:  R A Bloodgood; E M Leffler; A T Bojczuk
Journal:  J Cell Biol       Date:  1979-09       Impact factor: 10.539

8.  The calcium current of Helix neuron.

Authors:  N Akaike; K S Lee; A M Brown
Journal:  J Gen Physiol       Date:  1978-05       Impact factor: 4.086

9.  Tipping and mating-structure activation induced in Chlamydomonas gametes by flagellar membrane antisera.

Authors:  U W Goodenough; D Jurivich
Journal:  J Cell Biol       Date:  1978-12       Impact factor: 10.539

10.  Flagellar elongation and shortening in Chlamydomonas. The use of cycloheximide and colchicine to study the synthesis and assembly of flagellar proteins.

Authors:  J L Rosenbaum; J E Moulder; D L Ringo
Journal:  J Cell Biol       Date:  1969-05       Impact factor: 10.539

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  380 in total

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Authors:  P D Taulman; C J Haycraft; D F Balkovetz; B K Yoder
Journal:  Mol Biol Cell       Date:  2001-03       Impact factor: 4.138

2.  Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas.

Authors:  M E Porter; R Bower; J A Knott; P Byrd; W Dentler
Journal:  Mol Biol Cell       Date:  1999-03       Impact factor: 4.138

Review 3.  Biology and mechanism of trypanosome cell motility.

Authors:  Kent L Hill
Journal:  Eukaryot Cell       Date:  2003-04

Review 4.  Kinesin motors and primary cilia.

Authors:  Kristen J Verhey; John Dishinger; Hooi Lynn Kee
Journal:  Biochem Soc Trans       Date:  2011-10       Impact factor: 5.407

5.  IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.

Authors:  Daisy Xin; Kasey J Christopher; Lewie Zeng; Yong Kong; Scott D Weatherbee
Journal:  Development       Date:  2017-03-06       Impact factor: 6.868

6.  Protein kinase involved in flagellar-length control.

Authors:  Martin Wiese; Daniela Kuhn; Christoph G Grünfelder
Journal:  Eukaryot Cell       Date:  2003-08

Review 7.  Polycystin-2--an intracellular or plasma membrane channel?

Authors:  Ralph Witzgall
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-04       Impact factor: 3.000

8.  Identification of the TTC26 Splice Variant in a Novel Complex Ciliopathy Syndrome with Biliary, Renal, Neurological, and Skeletal Manifestations.

Authors:  Majid Alfadhel; Muhammad Umair; Bader Almuzzaini; Abdulaziz Asiri; Abeer Al Tuwaijri; Khaloud Alhamoudi; Yusra Alyafee; Mohammed Al-Owain
Journal:  Mol Syndromol       Date:  2021-05-11

9.  Analysis of KIF17 distal tip trafficking in zebrafish cone photoreceptors.

Authors:  Jason R Bader; Brandon W Kusik; Joseph C Besharse
Journal:  Vision Res       Date:  2012-10-23       Impact factor: 1.886

Review 10.  The Lateral Organization and Mobility of Plasma Membrane Components.

Authors:  Ken Jacobson; Ping Liu; B Christoffer Lagerholm
Journal:  Cell       Date:  2019-05-02       Impact factor: 41.582

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