Literature DB >> 8515521

The pH of secretions in sinusitis and otitis media.

J Nuutinen1, T Torkkeli, I Penttilä.   

Abstract

Impaired mucociliary function is a common finding in patients with recurrent respiratory infections, sinusitis and otitis media. One main component of mucociliary transport, ciliary beating activity, is sensitive to environmental hydrogen ion concentration (pH). The pH of secretion in 103 specimens from acute or chronic sinusitis and in 98 specimens from acute or secretory otitis media were measured. There were no differences between acute and chronic sinusitis (mean of pH 7.5 +/- 0.5 and 7.4 +/- 0.6) or between mucous and purulent secretions. In acute otitis media, secretion was significantly more acidic than in secretory otitis media (mean of pH 7.7 +/- 0.5 versus 8.2 +/- 0.4). The pH was less than 7.0 in 16 (15.5%) patients with chronic sinusitis and in two (8%) patients with acute otitis. The study shows that pH of sinusal or tympanal secretion is, in the majority of patients, within limits that do not cause ciliostasis.

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Year:  1993        PMID: 8515521

Source DB:  PubMed          Journal:  J Otolaryngol        ISSN: 0381-6605


  5 in total

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Authors:  Laura A Novotny; Kenneth L Brockman; Elaine M Mokrzan; Joseph A Jurcisek; Lauren O Bakaletz
Journal:  J Pediatr Infect Dis       Date:  2018-07-06       Impact factor: 0.293

2.  Expression of the Nontypeable Haemophilus influenzae Type IV Pilus Is Stimulated by Coculture with Host Respiratory Tract Epithelial Cells.

Authors:  Elaine M Mokrzan; Taylor J Johnson; Lauren O Bakaletz
Journal:  Infect Immun       Date:  2019-11-18       Impact factor: 3.441

3.  The ModA2 Phasevarion of nontypeable Haemophilus influenzae Regulates Resistance to Oxidative Stress and Killing by Human Neutrophils.

Authors:  Kenneth L Brockman; M Taylor Branstool; John M Atack; Frank Robledo-Avila; Santiago Partida-Sanchez; Michael P Jennings; Lauren O Bakaletz
Journal:  Sci Rep       Date:  2017-06-09       Impact factor: 4.379

4.  There is a specific response to pH by isolates of Haemophilus influenzae and this has a direct influence on biofilm formation.

Authors:  Nadiah Ishak; Alexandra Tikhomirova; Stephen J Bent; Garth D Ehrlich; Fen Z Hu; Stephen P Kidd
Journal:  BMC Microbiol       Date:  2014-02-21       Impact factor: 3.605

5.  Epigenetic Regulation Alters Biofilm Architecture and Composition in Multiple Clinical Isolates of Nontypeable Haemophilus influenzae.

Authors:  Kenneth L Brockman; Patrick N Azzari; M Taylor Branstool; John M Atack; Benjamin L Schulz; Freda E-C Jen; Michael P Jennings; Lauren O Bakaletz
Journal:  MBio       Date:  2018-09-18       Impact factor: 7.867

  5 in total

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