Literature DB >> 8514740

Isolation and characterization of a trisialyllactosylceramide, GT3, containing an O-acetylated sialic acid in cod fish brain.

H Waki1, A Murata, K Kon, K Maruyama, S Kimura, H Ogura, S Ando.   

Abstract

An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance spectroscopy in addition to chemical analysis. The structure was identified as a modified GT3 in which the external sialic acid is O-acetylated at the C-9 position. The chemical structure is as follows: II3(9-O-Ac-NeuAc2-8NeuAc2-8NeuAc2-3)Lac Cer.

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Year:  1993        PMID： 8514740     DOI： 10.1093/oxfordjournals.jbchem.a124073

Source DB:  PubMed          Journal:  J Biochem        ISSN： 0021-924X            Impact factor:   3.387


  6 in total

Review 1.  Sphingolipidomics: methods for the comprehensive analysis of sphingolipids.

Authors:  Christopher A Haynes; Jeremy C Allegood; Hyejung Park; M Cameron Sullards
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-12-31       Impact factor: 3.205

2.  Preparation of GM1 ganglioside with sialidase-producing marine bacteria as a microbial biocatalyst.

Authors:  Y Fukano; M Ito
Journal:  Appl Environ Microbiol       Date:  1997-05       Impact factor: 4.792

Review 3.  Gangliosides with O-acetylated sialic acids in tumors of neuroectodermal origin.

Authors:  Guido Kohla; Eggert Stockfleth; Roland Schauer
Journal:  Neurochem Res       Date:  2002-08       Impact factor: 3.996

4.  Developmentally regulated O-acetylated sialoglycans in the central nervous system revealed by a new monoclonal antibody 493D4 recognizing a wide range of O-acetylated glycoconjugates.

Authors:  G Zhang; L Ji; S Kurono; S C Fujita; S Furuya; Y Hirabayashi
Journal:  Glycoconj J       Date:  1997-11       Impact factor: 2.916

5.  Characterization of novel mono-O-acetylated GM3s containing 9-O-acetyl sialic acid and 6-O-acetyl galactose in equine erythrocytes.

Authors:  Y Yachida; K Tsuchihashi; S Gasa
Journal:  Glycoconj J       Date:  1996-04       Impact factor: 2.916

Review 6.  Development of miracle medicines from sialic acids.

Authors:  Haruo Ogura
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2011       Impact factor: 3.493
  6 in total

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