Literature DB >> 8514216

Dose-dependent genotoxic effect of pan masala and areca nut in the Salmonella typhimurium assay.

K Polasa1, S Babu, I S Shenolikar.   

Abstract

Aqueous extracts of different brands of pan masala and scented supari were tested for mutagenicity by the Salmonella typhimurium assay using tester strains TA98 and TA100. These extracts were found to be mutagenic to both tester strains. The mutagenic effects of pan masala and scented supari extracts were similar to that produced by areca nut extract. The addition of 500 ppm saccharin to the supari extracts did not alter the mutagenic response.

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Year:  1993        PMID: 8514216     DOI: 10.1016/0278-6915(93)90160-z

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  2 in total

Review 1.  Substance abuse: a pediatric concern.

Authors:  D R Patel; D E Greydanus
Journal:  Indian J Pediatr       Date:  1999 Jul-Aug       Impact factor: 1.967

2.  Analysis and Toxicity of Plain (PMP) and Blended (PMT) Indian Pan Masala (PM).

Authors:  Suresh Kumar Nigam; H Venkatakrishna-Bhatt
Journal:  Eurasian J Med       Date:  2013-02
  2 in total

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