Literature DB >> 8513139

Increased levels of NGF in sera of systemic lupus erythematosus patients.

L Bracci-Laudiero1, L Aloe, R Levi-Montalcini, M Galeazzi, D Schilter, J L Scully, U Otten.   

Abstract

Using a specific enzyme-linked immunosorbent assay (ELISA) for human nerve growth factor (NGF), serum levels in patients with systemic lupus erythematosus (SLE) were measured. We found a consistent increase in NGF levels in SLE patients compared with controls. A good correlation exists between serum NGF level and severity of clinical manifestation. We hypothesize that NGF might play a role in the pathogenesis of autoimmune disorders such as SLE.

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Year:  1993        PMID： 8513139     DOI： 10.1097/00001756-199305000-00025

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  20 in total

Review 1.  Neurotrophins and the immune system.

Authors:  José A Vega; Olivia García-Suárez; Jonas Hannestad; Marta Pérez-Pérez; Antonino Germanà
Journal:  J Anat       Date:  2003-07       Impact factor: 2.610

2.  Changes in plasma levels of BDNF and NGF reveal a gender-selective vulnerability to early adversity in rhesus macaques.

Authors:  Francesca Cirulli; Nadia Francia; Igor Branchi; Maria Teresa Antonucci; Luigi Aloe; Stephen J Suomi; Enrico Alleva
Journal:  Psychoneuroendocrinology       Date:  2008-10-11       Impact factor: 4.905

3.  Position-independent expression of a human nerve growth factor-luciferase reporter gene cloned on a yeast artificial chromosome vector.

Authors:  F A Asselbergs; R Grossenbacher; R Ortmann; B Hengerer; G K McMaster; E Sutter; R Widmer; F Buxton
Journal:  Nucleic Acids Res       Date:  1998-04-01       Impact factor: 16.971

4.  Increased circulating nerve growth factor is directly correlated with disease activity in juvenile chronic arthritis.

Authors:  F Falcini; M Matucci Cerinic; A Lombardi; S Generini; A Pignone; P Tirassa; M Ermini; L Lepore; G Partsch; L Aloe
Journal:  Ann Rheum Dis       Date:  1996-10       Impact factor: 19.103

5.  Time-course changes of nerve growth factor, corticotropin-releasing hormone, and nitric oxide synthase isoforms and their possible role in the development of inflammatory response in experimental allergic encephalomyelitis.

Authors:  L Calzà; L Giardino; M Pozza; A Micera; L Aloe
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

Review 6.  Nerve growth factor: a neurokine orchestrating neuroimmune-endocrine functions.

Authors:  S D Skaper
Journal:  Mol Neurobiol       Date:  2001 Aug-Dec       Impact factor: 5.590

7.  Chronic inflammation enhances NGF-β/TrkA system expression via EGFR/MEK/ERK pathway activation in Sjögren's syndrome.

Authors:  Sabrina Lisi; Margherita Sisto; Domenico Ribatti; Massimo D'Amore; Raffella De Lucro; Maria Antonia Frassanito; Loredana Lorusso; Angelo Vacca; Dario Domenico Lofrumento
Journal:  J Mol Med (Berl)       Date:  2014-02-21       Impact factor: 4.599

8.  Mast cells synthesize, store, and release nerve growth factor.

Authors:  A Leon; A Buriani; R Dal Toso; M Fabris; S Romanello; L Aloe; R Levi-Montalcini
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

9.  Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma.

Authors:  S Bonini; A Lambiase; S Bonini; F Angelucci; L Magrini; L Manni; L Aloe
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

10.  Low frequency of plasma nerve-growth factor detection is associated with death of memory B lymphocytes in HIV-1 infection.

Authors:  K Titanji; A Nilsson; C Mörch; A Samuelsson; A Sönnerborg; S Grutzmeier; M Zazzi; A De Milito
Journal:  Clin Exp Immunol       Date:  2003-05       Impact factor: 4.330
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