Literature DB >> 8512535

Genetics, systems, and alcohol.

G E McClearn1.   

Abstract

Under a variety of rubrics (e.g., complexity, self-constructing systems, dissipative structures), interest has recently burgeoned in applying principles of complex systems to a wide variety of scientific issues. A major concern is with emergent properties of systems not derivable from the properties of components of the systems. In this paper, some elementary aspects of "systems" considerations are applied to phenomena of alcohol pharmacogenetics. It is likely that whole new families of informative phenotypes can be generated by this approach.

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Year:  1993        PMID: 8512535     DOI: 10.1007/BF01067427

Source DB:  PubMed          Journal:  Behav Genet        ISSN: 0001-8244            Impact factor:   2.805


  7 in total

1.  The reliability and stability of biomarkers of aging.

Authors:  G E McClearn
Journal:  Ann N Y Acad Sci       Date:  1992-12-26       Impact factor: 5.691

Review 2.  Use of recombinant inbred strains to detect quantitative trait loci associated with behavior.

Authors:  R Plomin; G E McClearn; G Gora-Maslak; J M Neiderhiser
Journal:  Behav Genet       Date:  1991-03       Impact factor: 2.805

Review 3.  MOlecular democracy: who shares the controls?

Authors:  H Kacser; J A Burns
Journal:  Biochem Soc Trans       Date:  1979-10       Impact factor: 5.407

4.  Symposium IV: Diabetic syndrome in animals. Influence of genetic background on the expression of mutations at the diabetes locus in the mouse. II. Studies on background modifiers.

Authors:  D L Coleman; K P Hummel
Journal:  Isr J Med Sci       Date:  1975-07

5.  Reproducibility of ethanol elimination rates in long-sleep and short-sleep mice.

Authors:  A Smolen; T N Smolen
Journal:  J Stud Alcohol       Date:  1989-11

6.  Long-term repeatability of human alcohol metabolism, sensitivity and acute tolerance.

Authors:  C T Nagoshi; J R Wilson
Journal:  J Stud Alcohol       Date:  1989-03

7.  One-month repeatability of alcohol metabolism, sensitivity and acute tolerance.

Authors:  J R Wilson; C T Nagoshi
Journal:  J Stud Alcohol       Date:  1987-09
  7 in total

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