Literature DB >> 8511144

[Toxoplasmosis in pregnancy. Diagnosis and new therapeutic possibilities].

V Mirlesse1, F Jacquemard, F Daffos.   

Abstract

Congenital toxoplasmosis results from contamination of the foetus by Toxoplasma gondii during pregnancy. It is a frequent and severe condition calling for close surveillance of mothers at risk. During the last few years, numerous advances have been made in the diagnosis and treatment of toxoplasmosis. Its diagnosis in the mother is now more reliable due to improvements in serological techniques, while in the foetus the use of foetal vascular techniques has made it possible to detect those who are infected. Owing to a new and effective therapeutic method certain foetuses can now be treated successfully in utero, so that induced abortion is reserved to cases with severe and early toxoplasmosis. The contribution of new molecular biology techniques to advances in this ever moving field is explained.

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Year:  1993        PMID: 8511144

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  3 in total

1.  Early neonatal diagnosis of congenital toxoplasmosis: value of comparative enzyme-linked immunofiltration assay immunological profiles and anti-Toxoplasma gondii immunoglobulin M (IgM) or IgA immunocapture and implications for postnatal therapeutic strategies.

Authors:  J M Pinon; C Chemla; I Villena; F Foudrinier; D Aubert; D Puygauthier-Toubas; B Leroux; D Dupouy; C Quereux; M Talmud; T Trenque; G Potron; M Pluot; G Remy; A Bonhomme
Journal:  J Clin Microbiol       Date:  1996-03       Impact factor: 5.948

2.  Diagnosis of congenital toxoplasmosis by immunoblotting and relationship with other methods.

Authors:  B F Chumpitazi; A Boussaid; H Pelloux; C Racinet; M Bost; A Goullier-Fleuret
Journal:  J Clin Microbiol       Date:  1995-06       Impact factor: 5.948

3.  Evaluation of risk and diagnostic value of quantitative assays for anti-Toxoplasma gondii immunoglobulin A (IgA), IgE, and IgM and analytical study of specific IgG in immunodeficient patients.

Authors:  J M Pinon; F Foudrinier; G Mougeot; C Marx; D Aubert; O Toupance; G Niel; M Danis; P Camerlynck; G Remy
Journal:  J Clin Microbiol       Date:  1995-04       Impact factor: 5.948

  3 in total

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