Literature DB >> 85108

Severe malaria and glucose-6-phosphate-dehydrogenase deficiency: a reappraisal of the malaria/G-6-P.D. hypothesis.

S K Martin, L H Miller, D Alling, V C Okoye, G J Esan, B O Osunkoya, M Deane.   

Abstract

Nigerian children with convulsions and Plasmodium falciparium parasitaemia above 100,000/microliter did not show a decreased frequency of glucose-6-phosphate-dehydrogenase (G.-6-P.D.) deficiency. A re-evaluation of earlier studies has led to the conclusion that clinical evidence of protection against falciparum malaria in G.-6-P.D.-deficient individuals is lacking. Evidence for the possible role of malaria in selecting for G.-6-P.D.-deficient genes consists solely of the geographical association of high frequencies of G.-6-P.D. deficiency with endemic malaria.

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Year:  1979        PMID： 85108     DOI： 10.1016/s0140-6736(79)90946-2

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  9 in total

1.  Effect of red blood cell variants on childhood malaria in Mali: a prospective cohort study.

Authors:  Tatiana M Lopera-Mesa; Saibou Doumbia; Drissa Konaté; Jennifer M Anderson; Mory Doumbouya; Abdoul S Keita; Seidina A S Diakité; Karim Traoré; Michael A Krause; Ababacar Diouf; Samuel E Moretz; Gregory S Tullo; Kazutoyo Miura; Wenjuan Gu; Michael P Fay; Steve M Taylor; Carole A Long; Mahamadou Diakité; Rick M Fairhurst
Journal:  Lancet Haematol       Date:  2015-03-24       Impact factor: 18.959

2.  Glucose-6-phosphate dehydrogenase deficiency and susceptibility to childhood diseases in Kilifi, Kenya.

Authors:  Sophie Uyoga; Alex W Macharia; Carolyne M Ndila; Gideon Nyutu; Mohammed Shebe; Kennedy O Awuondo; Neema Mturi; Norbert Peshu; Benjamin Tsofa; J Anthony G Scott; Kathryn Maitland; Thomas N Williams
Journal:  Blood Adv       Date:  2020-12-08

3.  The relations between G-6-PD deficiency, thalassemia and malaria. Further analysis of data from Sardinia and the Po Valley.

Authors:  F Gloria-Bottini; A M Falsi; J Mortera; E Bottini
Journal:  Experientia       Date:  1980-05-15

4.  Associations between red cell polymorphisms and Plasmodium falciparum infection in the middle belt of Ghana.

Authors:  Nicholas Amoako; Kwaku Poku Asante; George Adjei; Gordon A Awandare; Langbong Bimi; Seth Owusu-Agyei
Journal:  PLoS One       Date:  2014-12-03       Impact factor: 3.240

5.  Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria.

Authors:  Hong Ming Huang; Denis C Bauer; Patrick M Lelliott; Matthew W A Dixon; Leann Tilley; Brendan J McMorran; Simon J Foote; Gaetan Burgio
Journal:  G3 (Bethesda)       Date:  2017-09-07       Impact factor: 3.154

6.  Glucose-6-phosphate dehydrogenase deficiency and reduced haemoglobin levels in African children with severe malaria.

Authors:  Christian N Nguetse; Christian G Meyer; Ayola Akim Adegnika; Tsiri Agbenyega; Bernhards R Ogutu; Peter G Kremsner; Thirumalaisamy P Velavan
Journal:  Malar J       Date:  2016-07-07       Impact factor: 2.979

7.  Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study.

Authors:  Sophie Uyoga; Carolyne M Ndila; Alex W Macharia; Gideon Nyutu; Shivang Shah; Norbert Peshu; Geraldine M Clarke; Dominic P Kwiatkowski; Kirk A Rockett; Thomas N Williams
Journal:  Lancet Haematol       Date:  2015-09-22       Impact factor: 30.153

8.  Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.

Authors:  Shivang S Shah; Kirk A Rockett; Muminatou Jallow; Fatou Sisay-Joof; Kalifa A Bojang; Margaret Pinder; Anna Jeffreys; Rachel Craik; Christina Hubbart; Thomas E Wellems; Dominic P Kwiatkowski
Journal:  Malar J       Date:  2016-01-07       Impact factor: 2.979

9.  High Incidence of Malaria Along the Sino-Burmese Border Is Associated With Polymorphisms of CR1, IL-1A, IL-4R, IL-4, NOS, and TNF, But Not With G6PD Deficiency.

Authors:  Na Ren; Ying-Min Kuang; Qiong-Lin Tang; Long Cheng; Chun-Hua Zhang; Zao-Qing Yang; Yong-Shu He; Yue-Chun Zhu
Journal:  Medicine (Baltimore)       Date:  2015-10       Impact factor: 1.817
  9 in total

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