Literature DB >> 8508684

Complementation analysis in ataxia telangiectasia: fibroblast-lymphoblastoid cell heterokaryon assay by radiation-induced chromosome aberrations.

P Chen1, C Kidson.   

Abstract

Using radiation-induced chromosome aberrations as a marker, heterokaryons of ataxia telangiectasia formed between appropriate combinations of lymphoblastoid cell lines (LCLs) and fibroblasts representing four and two different groups, respectively, were analyzed. The results showed that complementation group 2 in the LCL series corresponds to group D in the fibroblast series.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8508684     DOI： 10.1159/000133549

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  2 in total

1.  The gene for the ataxia-telangiectasia variant, Nijmegen breakage syndrome, maps to a 1-cM interval on chromosome 8q21.

Authors:  K Saar; K H Chrzanowska; M Stumm; M Jung; G Nürnberg; T F Wienker; E Seemanová; R D Wegner; A Reis; K Sperling
Journal:  Am J Hum Genet       Date:  1997-03       Impact factor: 11.025

2.  Noncomplementation of radiation-induced chromosome aberrations in ataxia-telangiectasia/ataxia-telangiectasia-variant heterodikaryons.

Authors:  M Stumm; K Sperling; R D Wegner
Journal:  Am J Hum Genet       Date:  1997-05       Impact factor: 11.025
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.