Literature DB >> 8508618

High prevalence of diabetes in chronic leg ulcer patients: a cross-sectional population study.

O Nelzén1, D Bergqvist, A Lindhagen.   

Abstract

In a cross-sectional survey, designed to detect all patients with current chronic leg ulcers, 27% of the patients had diabetes mellitus. The outcome for the 104 examined diabetic patients has been evaluated and compared with the 278 nondiabetic patients. The purpose was to establish the prevalence of leg ulcers among diabetic patients and to assess potential causes. The point prevalence was calculated by extrapolating the leg ulcer frequency to the total diabetic population in the studied area. The point prevalence for active leg ulcers (including foot ulcers) in diabetic patients was 3.5% (95% CI 2.8-4.2). Ulcers above the malleoli were almost as common as foot ulcers. Peripheral vascular disease was present in 67% of all ulcerated legs in patients with diabetes compared to 42% in nondiabetic patients (p < 0.001). In 72% of foot ulcers in diabetic patients arterial impairment was judged to be a contributing aetiological factor and in nondiabetic patients 45% (p < 0.001). Ulcers solely attributed to possible neuropathy were less common (15%). Ulcers with multifactorial causes were common above the malleoli. This survey has given the size of the problem and indicates macroangiopathy to be the dominating factor responsible for slow or nonhealing ulcers in diabetic patients. Objective assessment of arterial circulation is mandatory and signs of arterial impairment require consultation with a vascular surgeon.

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Year:  1993        PMID: 8508618     DOI: 10.1111/j.1464-5491.1993.tb00077.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  2 in total

1.  Feasibility of an electrostimulation system treatment for wound healing: a case series of patients with chronic ulcers in Barbados.

Authors:  Nkemcho Ojeh; Angela Rose; Selma Jackman; Morvillia Applewhaite; Veronica Webster
Journal:  Int Wound J       Date:  2015-03-10       Impact factor: 3.315

Review 2.  Leg Ulcers: A Report in Patients with Hemoglobin E Beta Thalassemia and Review of the Literature in Severe Beta Thalassemia.

Authors:  Vikita Mehta; Abirami Kirubarajan; Amir Sabouhanian; Sanasi M Jayawardena; Priya Chandrakumaran; Nila Thangavelu; Refai Cader; Sachith Mettananda; Dayananda Bandara; Shawn Khan; David J Weatherall; Angela Allen; Anuja P Premawardhena; Nancy F Olivieri
Journal:  Acta Haematol       Date:  2021-11-09       Impact factor: 3.068

  2 in total

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