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Literature DB >> 8508041

Association of anticholinergic activity of prescribed medications with postoperative delirium.

L Tune¹, S Carr, T Cooper, B Klug, R C Golinger.

Abstract

In a prior study, delirium and plasma anticholinergic drug levels were significantly correlated in 9 of 25 surgical intensive care patients. The present study, using cumulative anticholinergic effects of parent compounds of these patients' medications, found that delirious patients' medication combinations had significantly higher cumulative anticholinergic effects than those of nondelirious patients.

Entities: Disease Species

Mesh：

Substances：
Parasympatholytics

Year: 1993 PMID： 8508041 DOI： 10.1176/jnp.5.2.208

Source DB: PubMed Journal: J Neuropsychiatry Clin Neurosci ISSN： 0895-0172 Impact factor: 2.198

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Cited

12 in total

Review 1. Drug-induced delirium. Incidence, management and prevention.

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Journal: Drugs Aging Date: 2014-10 Impact factor: 3.923

Review 3. Delirium and sedation in the ICU.

Authors: Jennifer A Frontera
Journal: Neurocrit Care Date: 2011-06 Impact factor: 3.210

4. Pre- and post-transplantation risk factors for delirium onset and severity in patients undergoing hematopoietic stem-cell transplantation.

Authors: Jesse R Fann; Rebecca A Hubbard; Catherine M Alfano; Sari Roth-Roemer; Wayne J Katon; Karen L Syrjala
Journal: J Clin Oncol Date: 2011-01-24 Impact factor: 44.544

5. Association Between Perioperative Medication Use and Postoperative Delirium and Cognition in Older Adults Undergoing Elective Noncardiac Surgery.

Authors: Matthew S Duprey; John W Devlin; John L Griffith; Thomas G Travison; Becky A Briesacher; Richard Jones; Jane S Saczynski; Eva M Schmitt; Yun Gou; Edward R Marcantonio; Sharon K Inouye
Journal: Anesth Analg Date: 2022-02-24 Impact factor: 6.627

Association of anticholinergic activity of prescribed medications with postoperative delirium.

Review 1. Drug-induced delirium. Incidence, management and prevention.

2. Anticholinergic medications: an additional contributor to cognitive impairment in the heart failure population?

Review 3. Delirium and sedation in the ICU.

4. Pre- and post-transplantation risk factors for delirium onset and severity in patients undergoing hematopoietic stem-cell transplantation.

5. Association Between Perioperative Medication Use and Postoperative Delirium and Cognition in Older Adults Undergoing Elective Noncardiac Surgery.

Review 6. [Postoperative cognitive dysfunction].

7. Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population.

Review 8. Delirium in patients with cancer: assessment, impact, mechanisms and management.

Review 9. Cholinesterase inhibitors for delirium.

Review 10. Heart failure and cognitive impairment: challenges and opportunities.