Literature DB >> 8507399

Somatic mutation and memory.

C Berek1.   

Abstract

The germinal center plays a crucial role in the development of the memory B cell. The repertoire of the antigen-specific B cell is shaped in this microenvironment. Self-specific B cells escaping normal regulation may develop into high affinity pathogenic Ig-producing cells.

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Year:  1993        PMID： 8507399     DOI： 10.1016/0952-7915(93)90007-f

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  7 in total

1.  Regulation of memory B-cell survival by the BH3-only protein Puma.

Authors:  Cyril Clybouw; Silke Fischer; Marie Thérèse Auffredou; Patricia Hugues; Catherine Alexia; Philippe Bouillet; Martine Raphael; Gérald Leca; Andreas Strasser; David M Tarlinton; Aimé Vazquez
Journal:  Blood       Date:  2011-08-25       Impact factor: 22.113

2.  Structural repertoire in human VL pseudogenes of immunoglobulins: comparison with functional germline genes and amino acid sequences.

Authors:  J C Almagro; V Domínguez-Martinez; F Lara-Ochoa; E Vargas-Madrazo
Journal:  Immunogenetics       Date:  1996       Impact factor: 2.846

Review 3.  Effects of acute and chronic inflammation on B-cell development and differentiation.

Authors:  Derek Cain; Motonari Kondo; Huaiyong Chen; Garnett Kelsoe
Journal:  J Invest Dermatol       Date:  2009-02       Impact factor: 8.551

4.  Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin.

Authors:  I G Azcárate; P Marín-García; N Camacho; S Pérez-Benavente; A Puyet; A Diez; L Ribas de Pouplana; J M Bautista
Journal:  Br J Pharmacol       Date:  2013-06       Impact factor: 8.739

5.  In vitro evolution of single-chain antibodies using mRNA display.

Authors:  Isao Fukuda; Kanehisa Kojoh; Noriko Tabata; Nobuhide Doi; Hideaki Takashima; Etsuko Miyamoto-Sato; Hiroshi Yanagawa
Journal:  Nucleic Acids Res       Date:  2006-09-29       Impact factor: 16.971

6.  Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes.

Authors:  P C Wilson; O de Bouteiller; Y J Liu; K Potter; J Banchereau; J D Capra; V Pascual
Journal:  J Exp Med       Date:  1998-01-05       Impact factor: 14.307

7.  Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells.

Authors:  D K Dunn-Walters; P G Isaacson; J Spencer
Journal:  J Exp Med       Date:  1995-08-01       Impact factor: 14.307
  7 in total

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