Literature DB >> 8504483

Detection of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in beer and wine.

S Manabe1, H Suzuki, O Wada, A Ueki.   

Abstract

A carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), was measured in beer and wine by HPLC. PhIP was found to be present in all brands of beer and wine analyzed. The concentrations of PhIP in beer and wine were 14.1 +/- 6.18 ng/l (mean +/- SD, n = 11) and 30.4 +/- 16.4 ng/l (n = 10) respectively.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8504483     DOI： 10.1093/carcin/14.5.899

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN： 0143-3334            Impact factor:   4.944


  9 in total

1.  Detection of 2-amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine (PhIP)-DNA adducts in human pancreatic tissues.

Authors:  J Zhu; A Rashid; K Cleary; J L Abbruzzese; H Friess; S Takahashi; T Shirai; D Li
Journal:  Biomarkers       Date:  2006 Jul-Aug       Impact factor: 2.658

2.  Novel LC-ESI/MS/MS(n) method for the characterization and quantification of 2'-deoxyguanosine adducts of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by 2-D linear quadrupole ion trap mass spectrometry.

Authors:  Angela K Goodenough; Herman A J Schut; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2007-02       Impact factor: 3.739

3.  Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1.

Authors:  Kai Wang; F Peter Guengerich
Journal:  Chem Res Toxicol       Date:  2013-05-29       Impact factor: 3.739

4.  Non-covalent DNA groove-binding by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Authors:  G A Marsch; R L Ward; M Colvin; K W Turteltaub
Journal:  Nucleic Acids Res       Date:  1994-12-11       Impact factor: 16.971

5.  Biomonitoring of carcinogenic heterocyclic aromatic amines in hair: a validation study.

Authors:  Erin E Bessette; Isil Yasa; Deborah Dunbar; Lynne R Wilkens; Loic Le Marchand; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2009-08       Impact factor: 3.739

6.  Comparability and repeatability of methods for estimating the dietary intake of the heterocyclic amine contaminant 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP).

Authors:  Nicole C Deziel; Timothy J Buckley; Rashmi Sinha; Salahaddhin Abubaker; Elizabeth A Platz; Paul T Strickland
Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess       Date:  2012-05-09

7.  Determination of Heterocyclic Amines and Acrylamide in Agricultural Products with Liquid Chromatography-Tandem Mass Spectrometry.

Authors:  Kyung-Jun Lee; Gae-Ho Lee; HaeSol Kim; Min-Seok Oh; Seok Chu; In Ju Hwang; Jee-Yeon Lee; Ari Choi; Cho-Il Kim; Hyun-Mee Park
Journal:  Toxicol Res       Date:  2015-09

8.  Immunohistochemical detection of carcinogen-DNA adducts in normal human prostate tissues transplanted into the subcutis of athymic nude mice: results with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 3,2'-dimethyl-4-aminobiphenyl (DMAB) and relation to cytochrome P450s and N-acetyltransferase activity.

Authors:  L Cui; S Takahashi; M Tada; K Kato; Y Yamada; K Kohri; T Shirai
Journal:  Jpn J Cancer Res       Date:  2000-01

9.  Dose-dependent induction of mammary carcinomas in female Sprague-Dawley rats with 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine.

Authors:  K Imaida; A Hagiwara; H Yada; T Masui; R Hasegawa; M Hirose; T Sugimura; N Ito; T Shirai
Journal:  Jpn J Cancer Res       Date:  1996-11
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.